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Tumor DNA Instability Test

North Carolina rates for HCPCS 81301

This test examines a tumor sample for a pattern of genetic instability that occurs when the cells lose the ability to properly repair small errors in their DNA. Finding this pattern can point to an inherited cancer risk syndrome and can also help guide certain treatment decisions, including whether a specific type of cancer treatment is likely to work well. Tumor tissue is often compared against normal tissue from the same person for an accurate result.

Rates data updated July 2026.

How much does Tumor DNA Instability Test cost?

$282

Typical negotiated rate. In North Carolina, July 2026.

Insurers have agreed to pay about $282 for this service. The price depends on where it is billed: about $282 from a physician practice, and about $331 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$282$200 to $347
FacilityA hospital or hospital-owned outpatient department$331$302 to $355

How much rates vary

Facilitymedian $331 · 10th to 90th $282 to $603Professionalmedian $282 · 10th to 90th $174 to $457
$10.0$100.0$1.0K$10.0Kfacility $331professional $282

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$281.84
Median
$331.13
Typical High
$524.81
Aetna
Setting
Professional
Modifier
Global
Typical Low
$234.42
Median
$281.84
Typical High
$457.09
BCBS
Setting
Facility
Modifier
Global
Typical Low
$794.33
Median
$1,202.26
Typical High
$1,202.26
BCBS
Setting
Professional
Modifier
Global
Typical Low
$158.49
Median
$257.04
Typical High
$562.34
Cigna
Setting
Facility
Modifier
Global
Typical Low
$239.88
Median
$758.58
Typical High
$1,584.89
Cigna
Setting
Professional
Modifier
Global
Typical Low
$162.18
Median
$181.97
Typical High
$467.74
Medcost
Setting
Facility
Modifier
Global
Typical Low
$281.84
Median
$331.13
Typical High
$537.03
Medcost
Setting
Professional
Modifier
Global
Typical Low
$346.74
Median
$346.74
Typical High
$346.74
United
Setting
Facility
Modifier
Global
Typical Low
$234.42
Median
$407.38
Typical High
$524.81
United
Setting
Professional
Modifier
Global
Typical Low
$147.91
Median
$208.93
Typical High
$398.11
Wellcare
Setting
Facility
Modifier
Global
Typical Low
$1,659.59
Median
$1,659.59
Typical High
$1,659.59
Wellcare
Setting
Professional
Modifier
Global
Typical Low
$1,737.80
Median
$1,737.80
Typical High
$2,630.27

Where North Carolina sits

The same service costs 3.3 times more in Alaska than in Vermont. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

North Carolina $282 · 44th of 51
AK $776VT $234

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.