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Tumor DNA Instability Test

Maryland rates for HCPCS 81301

This test examines a tumor sample for a pattern of genetic instability that occurs when the cells lose the ability to properly repair small errors in their DNA. Finding this pattern can point to an inherited cancer risk syndrome and can also help guide certain treatment decisions, including whether a specific type of cancer treatment is likely to work well. Tumor tissue is often compared against normal tissue from the same person for an accurate result.

Rates data updated July 2026.

How much does Tumor DNA Instability Test cost?

$263

Typical negotiated rate. In Maryland, July 2026.

Insurers have agreed to pay about $263 for this service. Most negotiated rates run $229 to $324.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $832 · 10th to 90th $148 to $832Professionalmedian $263 · 10th to 90th $166 to $724
$200$500$1K$2Kfacility $832professional $263

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$302.00
Median
$831.76
Typical High
$831.76
Aetna
Setting
Professional
Modifier
Global
Typical Low
$257.04
Median
$288.40
Typical High
$724.44
CareFirst
Setting
Professional
Modifier
Global
Typical Low
$251.19
Median
$251.19
Typical High
$309.03
Cigna
Setting
Professional
Modifier
Global
Typical Low
$190.55
Median
$229.09
Typical High
$616.60
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$346.74
Median
$416.87
Typical High
$524.81
United
Setting
Facility
Modifier
Global
Typical Low
$147.91
Median
$147.91
Typical High
$1,778.28
United
Setting
Professional
Modifier
Global
Typical Low
$154.88
Median
$173.78
Typical High
$309.03
Wellpoint
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$281.84
Typical High
$281.84

Where Maryland sits

The same service costs 3.3 times more in Alaska than in Vermont. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Maryland· 50th of 51

$263

AK $776VT $234

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.