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Tumor DNA Instability Test

Alabama rates for HCPCS 81301

This test examines a tumor sample for a pattern of genetic instability that occurs when the cells lose the ability to properly repair small errors in their DNA. Finding this pattern can point to an inherited cancer risk syndrome and can also help guide certain treatment decisions, including whether a specific type of cancer treatment is likely to work well. Tumor tissue is often compared against normal tissue from the same person for an accurate result.

Rates data updated October 2026.

How much does Tumor DNA Instability Test cost?

$174

Typical negotiated rate. In Alabama, October 2026.

Insurers have agreed to pay about $174 for this service. The price depends on where it is billed: about $234 from a physician practice, and about $174 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$234$166 to $398
FacilityA hospital or hospital-owned outpatient department$174$174 to $174

How much rates vary

Facilitymedian $174 · 10th to 90th $174 to $295Professionalmedian $234 · 10th to 90th $148 to $398
$200$500$1Kfacility $174professional $234

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$398.11
Median
$398.11
Typical High
$537.03
Aetna
Setting
Professional
Modifier
None
Typical Low
$239.88
Median
$398.11
Typical High
$398.11
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$134.90
Median
$199.53
Typical High
$199.53
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$54.95
Median
$79.43
Typical High
$79.43
BCBS Alabama
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$173.78
Typical High
$173.78
BCBS Alabama
Setting
Professional
Modifier
21 + 22 · Increased work + 24 · Unrelated visit after surgery + 31
Typical Low
$309.03
Median
$346.74
Typical High
$346.74
Cigna
Setting
Facility
Modifier
None
Typical Low
$281.84
Median
$295.12
Typical High
$1,096.48
Cigna
Setting
Professional
Modifier
None
Typical Low
$147.91
Median
$173.78
Typical High
$1,659.59
United
Setting
Facility
Modifier
None
Typical Low
$125.89
Median
$316.23
Typical High
$346.74
United
Setting
Professional
Modifier
None
Typical Low
$147.91
Median
$208.93
Typical High
$234.42

Where Alabama sits

The same service costs 4.5 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Alabama· 51st of 51

$174

AK $776AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.