go back

MSH2 Large Deletion and Duplication Test

South Dakota rates for HCPCS 81297

A genetic test that checks the MSH2 gene for whole sections that are missing or present in extra copies. Faults in this gene cause Lynch syndrome, an inherited condition that raises the risk of bowel, womb and several other cancers. It looks for large blocks gained or lost rather than small single-letter spelling changes.

Rates data updated July 2026.

How much does MSH2 Large Deletion and Duplication Test cost?

$324

Typical negotiated rate. In South Dakota, July 2026.

Insurers have agreed to pay about $324 for this service. The price depends on where it is billed: about $302 from a physician practice, and about $407 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$302$166 to $501
FacilityA hospital or hospital-owned outpatient department$407$389 to $407

How much rates vary

Facilitymedian $407 · 10th to 90th $240 to $407Professionalmedian $302 · 10th to 90th $145 to $562
$100.0$200.0$500.0$1.0Kfacility $407professional $302

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$147.91
Median
$245.47
Typical High
$245.47
Aetna
Setting
Professional
Modifier
Global
Typical Low
$144.54
Median
$165.96
Typical High
$199.53
Cigna
Setting
Facility
Modifier
Global
Typical Low
$407.38
Median
$407.38
Typical High
$407.38
Cigna
Setting
Professional
Modifier
Global
Typical Low
$309.03
Median
$407.38
Typical High
$512.86
Medica
Setting
Facility
Modifier
Global
Typical Low
$177.83
Median
$239.88
Typical High
$416.87
Medica
Setting
Professional
Modifier
Global
Typical Low
$77.62
Median
$89.13
Typical High
$1,071.52
Sanford Health Plan
Setting
Professional
Modifier
Global
Typical Low
$302.00
Median
$501.19
Typical High
$588.84
United
Setting
Professional
Modifier
Global
Typical Low
$77.62
Median
$128.82
Typical High
$245.47
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$213.80
Median
$213.80
Typical High
$213.80

Where South Dakota sits

The same service costs 3.2 times more in Alaska than in North Dakota. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

South Dakota $324 · 5th of 51
AK $479ND $151

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.