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Tumor Gene Silencing (Methylation) Test

Hawaii rates for HCPCS 81288

A laboratory test on tumor tissue that checks whether the control switch of a particular gene has been chemically tagged and shut off, rather than altered in its sequence. A gene switched off this way behaves as though it were missing. Knowing that it has been silenced within the tumor can affect how the cancer is expected to respond to treatment and whether inherited risk should be looked into.

Rates data updated July 2026.

How much does Tumor Gene Silencing (Methylation) Test cost?

$229

Typical negotiated rate. In Hawaii, July 2026.

Insurers have agreed to pay about $229 for this service. Most negotiated rates run $191 to $240.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $191 · 10th to 90th $158 to $229Professionalmedian $240 · 10th to 90th $191 to $347
$200facility $191professional $240

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$158.49
Median
$190.55
Typical High
$229.09
Aetna
Setting
Professional
Modifier
Global
Typical Low
$239.88
Median
$239.88
Typical High
$239.88
Cigna
Setting
Professional
Modifier
Global
Typical Low
$229.09
Median
$229.09
Typical High
$229.09
HMSA
Setting
Professional
Modifier
Global
Typical Low
$190.55
Median
$229.09
Typical High
$239.88
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$213.80
Median
$229.09
Typical High
$288.40
United
Setting
Professional
Modifier
Global
Typical Low
$91.20
Median
$199.53
Typical High
$229.09
University Health Alliance
Setting
Professional
Modifier
Global
Typical Low
$162.18
Median
$281.84
Typical High
$389.05

Where Hawaii sits

The same service costs 3.0 times more in Alaska than in Maryland. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Hawaii· 17th of 51

$229

AK $437MD $145

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.