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Gene Test For Additional Tumor Mutations

Minnesota rates for HCPCS 81276

This laboratory test examines a tumor sample for gene changes beyond the handful of well-known ones checked first. Certain changes affect whether specific targeted cancer drugs, most often used for colorectal cancer, are likely to help. The sample tested is usually tumor tissue taken during a biopsy or surgery rather than blood.

Rates data updated October 2026.

How much does Gene Test For Additional Tumor Mutations cost?

$214

Typical negotiated rate. In Minnesota, October 2026.

Insurers have agreed to pay about $214 for this service. The price depends on where it is billed: about $195 from a physician practice, and about $380 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$195$166 to $234
FacilityA hospital or hospital-owned outpatient department$380$195 to $692

How much rates vary

Facilitymedian $380 · 10th to 90th $182 to $977Professionalmedian $195 · 10th to 90th $107 to $389
$100$200$500$1Kfacility $380professional $195

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$181.97
Median
$380.19
Typical High
$977.24
Aetna
Setting
Professional
Modifier
None
Typical Low
$181.97
Median
$181.97
Typical High
$234.42
BCBS Minnesota
Setting
Facility
Modifier
None
Typical Low
$181.97
Median
$194.98
Typical High
$467.74
BCBS Minnesota
Setting
Professional
Modifier
None
Typical Low
$154.88
Median
$173.78
Typical High
$194.98
Cigna
Setting
Facility
Modifier
None
Typical Low
$380.19
Median
$616.60
Typical High
$1,819.70
Cigna
Setting
Professional
Modifier
None
Typical Low
$223.87
Median
$251.19
Typical High
$371.54
Health Partners
Setting
Facility
Modifier
None
Typical Low
$363.08
Median
$588.84
Typical High
$1,412.54
Health Partners
Setting
Professional
Modifier
None
Typical Low
$223.87
Median
$223.87
Typical High
$371.54
Medica
Setting
Facility
Modifier
None
Typical Low
$234.42
Median
$354.81
Typical High
$398.11
Medica
Setting
Professional
Modifier
None
Typical Low
$102.33
Median
$199.53
Typical High
$977.24
United
Setting
Facility
Modifier
None
Typical Low
$194.98
Median
$194.98
Typical High
$234.42
United
Setting
Professional
Modifier
None
Typical Low
$81.28
Median
$154.88
Typical High
$457.09
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$91.20
Median
$91.20
Typical High
$91.20
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$36.31
Median
$36.31
Typical High
$36.31
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$91.20
Median
$91.20
Typical High
$114.82
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$36.31
Median
$36.31
Typical High
$46.77

Where Minnesota sits

The same service costs 3.7 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Minnesota· 15th of 51

$214

AK $437DE $117

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.