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Gene Test For A Mutation Linked To Mast Cell Disease

Pennsylvania rates for HCPCS 81273

This laboratory test examines a specific gene for a change associated with a mast cell condition, in which the body produces too many mast cells or these cells become overactive. The test looks at a particular section of the gene most likely to carry this disease-related change rather than sequencing the entire gene. Results can help guide decisions about treatments that target this specific gene change.

Rates data updated October 2026.

How much does Gene Test For A Mutation Linked To Mast Cell Disease cost?

$107

Typical negotiated rate. In Pennsylvania, October 2026.

Insurers have agreed to pay about $107 for this service. The price depends on where it is billed: about $100 from a physician practice, and about $170 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 11 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$100$93.33 to $126
FacilityA hospital or hospital-owned outpatient department$170$126 to $363

How much rates vary

Facilitymedian $170 · 10th to 90th $100 to $646Professionalmedian $100 · 10th to 90th $63 to $186
$100$200$500$1K$2K$5Kfacility $170professional $100

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$100.00
Median
$107.15
Typical High
$363.08
Aetna
Setting
Professional
Modifier
None
Typical Low
$97.72
Median
$100.00
Typical High
$107.15
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$48.98
Median
$50.12
Typical High
$52.48
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$19.95
Median
$20.42
Typical High
$21.38
AmeriHealth
Setting
Facility
Modifier
None
Typical Low
$81.28
Median
$162.18
Typical High
$1,318.26
Capital Blue Cross
Setting
Facility
Modifier
None
Typical Low
$489.78
Median
$630.96
Typical High
$5,011.87
Capital Blue Cross
Setting
Professional
Modifier
None
Typical Low
$87.10
Median
$97.72
Typical High
$302.00
Cigna
Setting
Facility
Modifier
None
Typical Low
$123.03
Median
$204.17
Typical High
$380.19
Cigna
Setting
Professional
Modifier
None
Typical Low
$57.54
Median
$117.49
Typical High
$190.55
Emblem Health
Setting
Professional
Modifier
None
Typical Low
$87.10
Median
$162.18
Typical High
$162.18
Geisinger
Setting
Facility
Modifier
None
Typical Low
$125.89
Median
$125.89
Typical High
$125.89
Geisinger
Setting
Professional
Modifier
None
Typical Low
$93.33
Median
$144.54
Typical High
$245.47
Highmark BCBS
Setting
Facility
Modifier
None
Typical Low
$61.66
Median
$245.47
Typical High
$549.54
Independence Blue Cross
Setting
Facility
Modifier
None
Typical Low
$102.33
Median
$158.49
Typical High
$331.13
Independence Blue Cross
Setting
Professional
Modifier
None
Typical Low
$125.89
Median
$125.89
Typical High
$125.89
Martin's Point
Setting
Facility
Modifier
None
Typical Low
$100.00
Median
$100.00
Typical High
$426.58
Martin's Point
Setting
Professional
Modifier
None
Typical Low
$97.72
Median
$100.00
Typical High
$107.15
Martin's Point
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$48.98
Median
$50.12
Typical High
$52.48
Martin's Point
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$19.95
Median
$20.42
Typical High
$21.38
UPMC Health Plan
Setting
Facility
Modifier
None
Typical Low
$125.89
Median
$389.05
Typical High
$870.96
UPMC Health Plan
Setting
Professional
Modifier
None
Typical Low
$125.89
Median
$138.04
Typical High
$138.04
United
Setting
Facility
Modifier
None
Typical Low
$112.20
Median
$125.89
Typical High
$151.36
United
Setting
Professional
Modifier
None
Typical Low
$52.48
Median
$74.13
Typical High
$151.36

Where Pennsylvania sits

The same service costs 4.5 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Pennsylvania· 37th of 51

$107

AK $282AL $63.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.