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JAK2 V617F Gene Change Test

West Virginia rates for HCPCS 81270

Looks in a blood or bone-marrow sample for one specific change in the JAK2 gene, known as V617F, which drives the marrow to overproduce blood cells. Finding it supports the diagnosis of a myeloproliferative disorder such as polycythemia vera, essential thrombocythemia or myelofibrosis. The change is picked up during life in the blood-forming cells rather than inherited.

Rates data updated July 2026.

Facilitymedian $794 · 10th–90th $115$1,3490%10%10th90th$794Professionalmedian $74 · 10th–90th $62$870%20%40%10th90th$74$50.0$100.0$200.0$500.0$1.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$138.04
Median
$794.33
Typical High
$1,348.96
Aetna
Setting
Professional
Modifier
Global
Typical Low
$61.66
Median
$74.13
Typical High
$87.10
CareSource
Setting
Facility
Modifier
Global
Typical Low
$123.03
Median
$123.03
Typical High
$123.03
CareSource
Setting
Professional
Modifier
Global
Typical Low
$91.20
Median
$109.65
Typical High
$151.36
Cigna
Setting
Facility
Modifier
Global
Typical Low
$89.13
Median
$199.53
Typical High
$275.42
Cigna
Setting
Professional
Modifier
Global
Typical Low
$162.18
Median
$446.68
Typical High
$446.68
Highmark BCBS
Setting
Facility
Modifier
Global
Typical Low
$295.12
Median
$398.11
Typical High
$660.69
United
Setting
Facility
Modifier
Global
Typical Low
$38.90
Median
$38.90
Typical High
$104.71
United
Setting
Professional
Modifier
Global
Typical Low
$41.69
Median
$52.48
Typical High
$125.89