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JAK2 V617F Gene Change Test

Connecticut rates for HCPCS 81270

Looks in a blood or bone-marrow sample for one specific change in the JAK2 gene, known as V617F, which drives the marrow to overproduce blood cells. Finding it supports the diagnosis of a myeloproliferative disorder such as polycythemia vera, essential thrombocythemia or myelofibrosis. The change is picked up during life in the blood-forming cells rather than inherited.

Rates data updated July 2026.

Facilitymedian $155 · 10th–90th $91$2690%10%10th90th$155Professionalmedian $83 · 10th–90th $58$2750%10%20%10th90th$83$50.0$100.0$200.0$500.0$1.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$91.20
Median
$162.18
Typical High
$275.42
Aetna
Setting
Professional
Modifier
Global
Typical Low
$60.26
Median
$83.18
Typical High
$288.40
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$54.95
Median
$144.54
Typical High
$245.47
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$41.69
Median
$58.88
Typical High
$223.87
Cigna
Setting
Facility
Modifier
Global
Typical Low
$91.20
Median
$154.88
Typical High
$363.08
Cigna
Setting
Professional
Modifier
Global
Typical Low
$56.23
Median
$109.65
Typical High
$213.80
ConnectiCare
Setting
Professional
Modifier
Global
Typical Low
$91.20
Median
$95.50
Typical High
$173.78
Health New England
Setting
Facility
Modifier
Global
Typical Low
$199.53
Median
$199.53
Typical High
$199.53
United
Setting
Facility
Modifier
Global
Typical Low
$91.20
Median
$91.20
Typical High
$91.20
United
Setting
Professional
Modifier
Global
Typical Low
$45.71
Median
$77.62
Typical High
$154.88