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JAK2 V617F Gene Change Test

Connecticut rates for HCPCS 81270

Looks in a blood or bone-marrow sample for one specific change in the JAK2 gene, known as V617F, which drives the marrow to overproduce blood cells. Finding it supports the diagnosis of a myeloproliferative disorder such as polycythemia vera, essential thrombocythemia or myelofibrosis. The change is picked up during life in the blood-forming cells rather than inherited.

Rates data updated October 2026.

How much does JAK2 V617F Gene Change Test cost?

$63.10

Typical negotiated rate. In Connecticut, October 2026.

Insurers have agreed to pay about $63.10 for this service. The price depends on where it is billed: about $57.54 from a physician practice, and about $107 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$57.54$46.77 to $83.18
FacilityA hospital or hospital-owned outpatient department$107$72.44 to $182

How much rates vary

Facilitymedian $107 · 10th to 90th $49 to $229Professionalmedian $58 · 10th to 90th $46 to $132
$50$100$200facility $107professional $58

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
None
Typical Low
$61.66
Median
$83.18
Typical High
$128.82
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$45.71
Median
$100.00
Typical High
$229.09
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$41.69
Median
$54.95
Typical High
$107.15
Cigna
Setting
Facility
Modifier
None
Typical Low
$91.20
Median
$144.54
Typical High
$363.08
Cigna
Setting
Professional
Modifier
None
Typical Low
$60.26
Median
$117.49
Typical High
$229.09
ConnectiCare
Setting
Professional
Modifier
None
Typical Low
$91.20
Median
$123.03
Typical High
$147.91
Health New England
Setting
Facility
Modifier
None
Typical Low
$199.53
Median
$199.53
Typical High
$199.53
United
Setting
Professional
Modifier
None
Typical Low
$38.90
Median
$56.23
Typical High
$125.89
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$33.88
Median
$41.69
Typical High
$41.69
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$13.49
Median
$16.60
Typical High
$16.60

Where Connecticut sits

The same service costs 3.2 times more in Alaska than in Connecticut. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Connecticut· 51st of 51

$63.10

AK $204CT $63.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.