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Targeted Analysis of a Single Gene

Colorado rates for HCPCS 81246

A laboratory test that examines one specific gene in a sample of blood, bone marrow, or tissue, looking at defined positions within it to see whether a change is present. The finding is reported alongside the other results being used to reach a diagnosis or plan treatment.

Rates data updated October 2026.

How much does Targeted Analysis of a Single Gene cost?

$110

Typical negotiated rate. In Colorado, October 2026.

Insurers have agreed to pay about $110 for this service. The price depends on where it is billed: about $50.12 from a physician practice, and about $240 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$50.12$34.67 to $107
FacilityA hospital or hospital-owned outpatient department$240$155 to $288

How much rates vary

Facilitymedian $240 · 10th to 90th $65 to $380Professionalmedian $50 · 10th to 90th $35 to $170
$50$100$200$500facility $240professional $50

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$83.18
Median
$173.78
Typical High
$380.19
Aetna
Setting
Professional
Modifier
None
Typical Low
$61.66
Median
$63.10
Typical High
$107.15
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$87.10
Median
$251.19
Typical High
$380.19
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$34.67
Median
$34.67
Typical High
$181.97
Cigna
Setting
Facility
Modifier
None
Typical Low
$48.98
Median
$100.00
Typical High
$263.03
Cigna
Setting
Professional
Modifier
None
Typical Low
$38.90
Median
$44.67
Typical High
$120.23
Denver HMP
Setting
Facility
Modifier
None
Typical Low
$63.10
Median
$74.13
Typical High
$102.33
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$83.18
Median
$117.49
Typical High
$213.80
Select Health
Setting
Facility
Modifier
None
Typical Low
$83.18
Median
$154.88
Typical High
$173.78
Select Health
Setting
Professional
Modifier
None
Typical Low
$57.54
Median
$83.18
Typical High
$125.89
United
Setting
Facility
Modifier
None
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
United
Setting
Professional
Modifier
None
Typical Low
$34.67
Median
$34.67
Typical High
$61.66
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$30.90
Median
$31.62
Typical High
$53.70
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$12.59
Median
$12.59
Typical High
$21.38

Where Colorado sits

The same service costs 3.4 times more in Alaska than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Colorado· 6th of 51

$110

AK $186NE $54.95

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.