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Fragile X Gene Test

Missouri rates for HCPCS 81243

A laboratory test on a blood sample that examines a specific gene on the X chromosome for an abnormally expanded stretch of repeated genetic letters. That expansion is the cause of fragile X syndrome, an inherited condition that can cause developmental delay and intellectual disability. The test identifies whether such an expansion is present.

Rates data updated October 2026.

How much does Fragile X Gene Test cost?

$54.95

Typical negotiated rate. In Missouri, October 2026.

Insurers have agreed to pay about $54.95 for this service. The price depends on where it is billed: about $48.98 from a physician practice, and about $100 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$48.98$33.88 to $89.13
FacilityA hospital or hospital-owned outpatient department$100$69.18 to $155

How much rates vary

Facilitymedian $100 · 10th to 90th $56 to $269Professionalmedian $49 · 10th to 90th $28 to $145
$50$100$200$500facility $100professional $49

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$48.98
Median
$74.13
Typical High
$104.71
Aetna
Setting
Professional
Modifier
None
Typical Low
$48.98
Median
$54.95
Typical High
$66.07
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$57.54
Median
$57.54
Typical High
$263.03
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$33.88
Median
$52.48
Typical High
$102.33
BCBS Kansas City
Setting
Facility
Modifier
None
Typical Low
$79.43
Median
$89.13
Typical High
$154.88
BCBS Kansas City
Setting
Professional
Modifier
None
Typical Low
$39.81
Median
$57.54
Typical High
$107.15
Cigna
Setting
Facility
Modifier
None
Typical Low
$77.62
Median
$128.82
Typical High
$316.23
Cigna
Setting
Professional
Modifier
None
Typical Low
$26.92
Median
$53.70
Typical High
$74.13
Medica
Setting
Facility
Modifier
None
Typical Low
$51.29
Median
$100.00
Typical High
$269.15
Medica
Setting
Professional
Modifier
None
Typical Low
$28.84
Median
$58.88
Typical High
$288.40
United
Setting
Facility
Modifier
None
Typical Low
$51.29
Median
$51.29
Typical High
$51.29
United
Setting
Professional
Modifier
None
Typical Low
$23.99
Median
$33.88
Typical High
$75.86
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$23.99
Median
$24.55
Typical High
$33.11
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$9.77
Median
$9.77
Typical High
$13.18

Where Missouri sits

The same service costs 3.4 times more in Alaska than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 34th of 51

$54.95

AK $129NE $38.02

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.