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Fragile X Gene Test

Illinois rates for HCPCS 81243

A laboratory test on a blood sample that examines a specific gene on the X chromosome for an abnormally expanded stretch of repeated genetic letters. That expansion is the cause of fragile X syndrome, an inherited condition that can cause developmental delay and intellectual disability. The test identifies whether such an expansion is present.

Rates data updated October 2026.

How much does Fragile X Gene Test cost?

$43.65

Typical negotiated rate. In Illinois, October 2026.

Insurers have agreed to pay about $43.65 for this service. The price depends on where it is billed: about $39.81 from a physician practice, and about $110 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$39.81$3.80 to $43.65
FacilityA hospital or hospital-owned outpatient department$110$77.62 to $191

How much rates vary

Facilitymedian $110 · 10th to 90th $65 to $347Professionalmedian $40 · 10th to 90th $3 to $74
$5$10$20$50$100$200$500facility $110professional $40

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$46.77
Median
$69.18
Typical High
$169.82
Aetna
Setting
Professional
Modifier
None
Typical Low
$42.66
Median
$46.77
Typical High
$54.95
BCBS Illinois
Setting
Facility
Modifier
None
Typical Low
$69.18
Median
$100.00
Typical High
$724.44
BCBS Illinois
Setting
Professional
Modifier
None
Typical Low
$3.47
Median
$39.81
Typical High
$43.65
Cigna
Setting
Facility
Modifier
None
Typical Low
$64.57
Median
$125.89
Typical High
$234.42
Cigna
Setting
Professional
Modifier
None
Typical Low
$28.84
Median
$77.62
Typical High
$95.50
Hally Health
Setting
Professional
Modifier
None
Typical Low
$63.10
Median
$91.20
Typical High
$457.09
Hally Health
Setting
Facility
Modifier
None
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Hally Health
Setting
Professional
Modifier
None
Typical Low
$74.13
Median
$74.13
Typical High
$74.13
United
Setting
Facility
Modifier
None
Typical Low
$57.54
Median
$69.18
Typical High
$70.79
United
Setting
Professional
Modifier
None
Typical Low
$23.99
Median
$33.88
Typical High
$57.54
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$23.44
Median
$45.71
Typical High
$87.10
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$9.33
Median
$18.20
Typical High
$34.67
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$23.44
Median
$23.44
Typical High
$25.70
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$9.33
Median
$9.33
Typical High
$10.23

Where Illinois sits

The same service costs 3.4 times more in Alaska than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Illinois· 49th of 51

$43.65

AK $129NE $38.02

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.