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Fragile X Gene Test

Colorado rates for HCPCS 81243

A laboratory test on a blood sample that examines a specific gene on the X chromosome for an abnormally expanded stretch of repeated genetic letters. That expansion is the cause of fragile X syndrome, an inherited condition that can cause developmental delay and intellectual disability. The test identifies whether such an expansion is present.

Rates data updated October 2026.

How much does Fragile X Gene Test cost?

$75.86

Typical negotiated rate. In Colorado, October 2026.

Insurers have agreed to pay about $75.86 for this service. The price depends on where it is billed: about $37.15 from a physician practice, and about $166 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$37.15$23.99 to $74.13
FacilityA hospital or hospital-owned outpatient department$166$105 to $200

How much rates vary

Facilitymedian $166 · 10th to 90th $44 to $263Professionalmedian $37 · 10th to 90th $24 to $117
$50$100$200$500facility $166professional $37

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$57.54
Median
$120.23
Typical High
$263.03
Aetna
Setting
Professional
Modifier
None
Typical Low
$42.66
Median
$43.65
Typical High
$87.10
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$60.26
Median
$169.82
Typical High
$263.03
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$23.99
Median
$23.99
Typical High
$125.89
Cigna
Setting
Facility
Modifier
None
Typical Low
$33.11
Median
$69.18
Typical High
$177.83
Cigna
Setting
Professional
Modifier
None
Typical Low
$26.30
Median
$39.81
Typical High
$83.18
Denver HMP
Setting
Facility
Modifier
None
Typical Low
$43.65
Median
$51.29
Typical High
$70.79
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$53.70
Median
$81.28
Typical High
$131.83
Select Health
Setting
Facility
Modifier
None
Typical Low
$57.54
Median
$104.71
Typical High
$120.23
Select Health
Setting
Professional
Modifier
None
Typical Low
$39.81
Median
$57.54
Typical High
$85.11
United
Setting
Facility
Modifier
None
Typical Low
$69.18
Median
$69.18
Typical High
$69.18
United
Setting
Professional
Modifier
None
Typical Low
$23.99
Median
$23.99
Typical High
$42.66
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$21.38
Median
$21.88
Typical High
$43.65
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$8.51
Median
$8.71
Typical High
$17.78

Where Colorado sits

The same service costs 3.4 times more in Alaska than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Colorado· 8th of 51

$75.86

AK $129NE $38.02

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.