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EZH2 Gene Full Sequence Test

Missouri rates for HCPCS 81236

A laboratory test that reads the complete sequence of the EZH2 gene in a blood or bone-marrow sample and reports any changes found. Changes in this gene occur in certain bone-marrow disorders and can help confirm a diagnosis.

Rates data updated October 2026.

How much does EZH2 Gene Full Sequence Test cost?

$275

Typical negotiated rate. In Missouri, October 2026.

Insurers have agreed to pay about $275 for this service. The price depends on where it is billed: about $257 from a physician practice, and about $490 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$257$170 to $457
FacilityA hospital or hospital-owned outpatient department$490$288 to $724

How much rates vary

Facilitymedian $490 · 10th to 90th $275 to $1,349Professionalmedian $257 · 10th to 90th $141 to $741
$200$500$1K$2Kfacility $490professional $257

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$239.88
Median
$363.08
Typical High
$524.81
Aetna
Setting
Professional
Modifier
None
Typical Low
$218.78
Median
$245.47
Typical High
$323.59
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$281.84
Median
$281.84
Typical High
$1,318.26
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$169.82
Median
$269.15
Typical High
$537.03
BCBS Kansas City
Setting
Facility
Modifier
None
Typical Low
$446.68
Median
$501.19
Typical High
$891.25
BCBS Kansas City
Setting
Professional
Modifier
None
Typical Low
$199.53
Median
$323.59
Typical High
$549.54
Cigna
Setting
Facility
Modifier
None
Typical Low
$288.40
Median
$616.60
Typical High
$1,445.44
Cigna
Setting
Professional
Modifier
None
Typical Low
$120.23
Median
$223.87
Typical High
$363.08
Medica
Setting
Facility
Modifier
None
Typical Low
$257.04
Median
$489.78
Typical High
$1,348.96
Medica
Setting
Professional
Modifier
None
Typical Low
$141.25
Median
$295.12
Typical High
$1,412.54
United
Setting
Facility
Modifier
None
Typical Low
$257.04
Median
$257.04
Typical High
$257.04
United
Setting
Professional
Modifier
None
Typical Low
$117.49
Median
$169.82
Typical High
$380.19
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$120.23
Median
$123.03
Typical High
$162.18
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$47.86
Median
$48.98
Typical High
$64.57

Where Missouri sits

The same service costs 3.7 times more in Alaska than in Oklahoma. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 27th of 51

$275

AK $631OK $170

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.