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EZH2 Gene Full Sequence Test

Massachusetts rates for HCPCS 81236

A laboratory test that reads the complete sequence of the EZH2 gene in a blood or bone-marrow sample and reports any changes found. Changes in this gene occur in certain bone-marrow disorders and can help confirm a diagnosis.

Rates data updated October 2026.

How much does EZH2 Gene Full Sequence Test cost?

$295

Typical negotiated rate. In Massachusetts, October 2026.

Insurers have agreed to pay about $295 for this service. The price depends on where it is billed: about $282 from a physician practice, and about $355 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 9 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$282$170 to $708
FacilityA hospital or hospital-owned outpatient department$355$282 to $513

How much rates vary

Facilitymedian $355 · 10th to 90th $209 to $871Professionalmedian $282 · 10th to 90th $170 to $1,413
$100$200$500$1K$2K$5Kfacility $355professional $282

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$199.53
Median
$398.11
Typical High
$891.25
Aetna
Setting
Professional
Modifier
None
Typical Low
$199.53
Median
$199.53
Typical High
$199.53
AllWays Health Partners
Setting
Facility
Modifier
None
Typical Low
$208.93
Median
$323.59
Typical High
$870.96
AllWays Health Partners
Setting
Professional
Modifier
None
Typical Low
$169.82
Median
$537.03
Typical High
$1,412.54
BCBS Massachusetts
Setting
Facility
Modifier
None
Typical Low
$281.84
Median
$354.81
Typical High
$707.95
BCBS Massachusetts
Setting
Professional
Modifier
None
Typical Low
$263.03
Median
$263.03
Typical High
$275.42
Cigna
Setting
Facility
Modifier
None
Typical Low
$186.21
Median
$218.78
Typical High
$501.19
Cigna
Setting
Professional
Modifier
None
Typical Low
$165.96
Median
$338.84
Typical High
$1,096.48
Fallon Health
Setting
Facility
Modifier
None
Typical Low
$147.91
Median
$478.63
Typical High
$5,888.44
Fallon Health
Setting
Professional
Modifier
None
Typical Low
$407.38
Median
$407.38
Typical High
$478.63
Harvard Pilgrim
Setting
Professional
Modifier
None
Typical Low
$169.82
Median
$281.84
Typical High
$741.31
Mass General Brigham
Setting
Facility
Modifier
None
Typical Low
$208.93
Median
$323.59
Typical High
$870.96
Mass General Brigham
Setting
Professional
Modifier
None
Typical Low
$169.82
Median
$537.03
Typical High
$1,412.54
United
Setting
Facility
Modifier
None
Typical Low
$257.04
Median
$281.84
Typical High
$338.84
United
Setting
Professional
Modifier
None
Typical Low
$112.20
Median
$169.82
Typical High
$537.03
Well Sense
Setting
Facility
Modifier
None
Typical Low
$251.19
Median
$346.74
Typical High
$512.86
Well Sense
Setting
Professional
Modifier
None
Typical Low
$2,511.89
Median
$2,511.89
Typical High
$3,019.95
3 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$39.81
Median
$39.81
Typical High
$39.81
Fallon Health
Setting
Facility
Modifier
QW · Waived lab test
Typical Low
$281.84
Median
$371.54
Typical High
$436.52

Where Massachusetts sits

The same service costs 3.7 times more in Alaska than in Oklahoma. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 19th of 51

$295

AK $631OK $170

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.