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BTK Gene Variant Test

Nebraska rates for HCPCS 81233

A laboratory test on a blood or bone marrow sample that looks for common changes in the BTK gene. Changes of this kind can appear in some blood cancers during treatment and make the cancer stop responding to a class of targeted drugs. The result helps decide whether to continue or switch treatment.

Rates data updated July 2026.

How much does BTK Gene Variant Test cost?

$166

Typical negotiated rate. In Nebraska, July 2026.

Insurers have agreed to pay about $166 for this service. The price depends on where it is billed: about $115 from a physician practice, and about $355 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$115$115 to $468
FacilityA hospital or hospital-owned outpatient department$355$123 to $468

How much rates vary

Facilitymedian $355 · 10th to 90th $105 to $692Professionalmedian $115 · 10th to 90th $105 to $1,148
$100$200$500$1Kfacility $355professional $115

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$123.03
Median
$467.74
Typical High
$870.96
Aetna
Setting
Professional
Modifier
Global
Typical Low
$114.82
Median
$114.82
Typical High
$1,148.15
BCBS
Setting
Facility
Modifier
Global
Typical Low
$338.84
Median
$436.52
Typical High
$851.14
BCBS
Setting
Professional
Modifier
Global
Typical Low
$251.19
Median
$275.42
Typical High
$288.40
Cigna
Setting
Professional
Modifier
Global
Typical Low
$208.93
Median
$338.84
Typical High
$416.87
Medica
Setting
Facility
Modifier
Global
Typical Low
$104.71
Median
$218.78
Typical High
$831.76
Medica
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$104.71
Typical High
$501.19
Midlands
Setting
Professional
Modifier
Global
Typical Low
$363.08
Median
$363.08
Typical High
$363.08
United
Setting
Facility
Modifier
Global
Typical Low
$74.13
Median
$165.96
Typical High
$173.78
United
Setting
Professional
Modifier
Global
Typical Low
$100.00
Median
$104.71
Typical High
$489.78

Where Nebraska sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Nebraska· 30th of 51

$166

AK $398DE $117

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.