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Full Cystic Fibrosis Gene Sequencing

Texas rates for HCPCS 81223

This laboratory test reads through the entire sequence of the gene most commonly associated with cystic fibrosis, looking for any disease-causing change rather than just the most frequent ones. It is used when a more limited screening test does not explain a person's symptoms or family history, or when a comprehensive result is specifically needed. The test can be run on a blood or saliva sample.

Rates data updated October 2026.

How much does Full Cystic Fibrosis Gene Sequencing cost?

$977

Typical negotiated rate. In Texas, October 2026.

Insurers have agreed to pay about $977 for this service. The price depends on where it is billed: about $617 from a physician practice, and about $1,445 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 11 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$617$282 to $2,512
FacilityA hospital or hospital-owned outpatient department$1,445$912 to $2,399

How much rates vary

Facilitymedian $1,445 · 10th to 90th $501 to $3,311Professionalmedian $617 · 10th to 90th $5 to $3,715
$10$100$1K$10Kfacility $1,445professional $617

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$331.13
Median
$724.44
Typical High
$2,691.53
Aetna
Setting
Professional
Modifier
None
Typical Low
$302.00
Median
$309.03
Typical High
$501.19
Ambetter
Setting
Professional
Modifier
None
Typical Low
$309.03
Median
$309.03
Typical High
$309.03
BCBS Texas
Setting
Facility
Modifier
None
Typical Low
$758.58
Median
$1,819.70
Typical High
$3,311.31
BCBS Texas
Setting
Professional
Modifier
None
Typical Low
$5.01
Median
$275.42
Typical High
$676.08
Cigna
Setting
Facility
Modifier
None
Typical Low
$323.59
Median
$1,000.00
Typical High
$1,548.82
Cigna
Setting
Professional
Modifier
None
Typical Low
$257.04
Median
$478.63
Typical High
$933.25
Lucent Health
Setting
Professional
Modifier
None
Typical Low
$2,511.89
Median
$3,715.35
Typical High
$3,715.35
Moda Health
Setting
Facility
Modifier
None
Typical Low
$331.13
Median
$602.56
Typical High
$2,511.89
Moda Health
Setting
Professional
Modifier
None
Typical Low
$302.00
Median
$309.03
Typical High
$501.19
Molina
Setting
Professional
Modifier
None
Typical Low
$416.87
Median
$416.87
Typical High
$501.19
Oscar Health
Setting
Professional
Modifier
None
Typical Low
$501.19
Median
$537.03
Typical High
$1,071.52
Providence
Setting
Facility
Modifier
None
Typical Low
$354.81
Median
$1,122.02
Typical High
$2,041.74
Providence
Setting
Professional
Modifier
None
Typical Low
$257.04
Median
$588.84
Typical High
$912.01
United
Setting
Facility
Modifier
None
Typical Low
$177.83
Median
$208.93
Typical High
$501.19
United
Setting
Professional
Modifier
None
Typical Low
$208.93
Median
$208.93
Typical High
$346.74
Wellpoint
Setting
Professional
Modifier
None
Typical Low
$257.04
Median
$501.19
Typical High
$676.08
8 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$165.96
Median
$363.08
Typical High
$1,348.96
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$67.61
Median
$144.54
Typical High
$537.03
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$151.36
Median
$158.49
Typical High
$234.42
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$60.26
Median
$63.10
Typical High
$93.33
Moda Health
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$190.55
Median
$363.08
Typical High
$1,348.96
Moda Health
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$75.86
Median
$144.54
Typical High
$537.03
Moda Health
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$151.36
Median
$154.88
Typical High
$199.53
Moda Health
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$60.26
Median
$61.66
Typical High
$79.43

Where Texas sits

The same service costs 3.8 times more in California than in Oklahoma. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Texas· 3rd of 51

$977

CA $1,202OK $316

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.