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Cystic Fibrosis Gene Test, Common Changes

Maryland rates for HCPCS 81220

This is a genetic test that checks for the most common changes in the gene linked to cystic fibrosis, an inherited condition that affects the lungs and digestive system. It is often used for carrier screening during family planning or pregnancy, as well as to help confirm a diagnosis.

Rates data updated October 2026.

How much does Cystic Fibrosis Gene Test, Common Changes cost?

$447

Typical negotiated rate. In Maryland, October 2026.

Insurers have agreed to pay about $447 for this service. Most negotiated rates run $372 to $501.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $447 · 10th to 90th $251 to $646
$500$1Kprofessional $447

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
None
Typical Low
$407.38
Median
$416.87
Typical High
$426.58
CareFirst
Setting
Professional
Modifier
None
Typical Low
$446.68
Median
$501.19
Typical High
$549.54
Cigna
Setting
Professional
Modifier
None
Typical Low
$295.12
Median
$537.03
Typical High
$1,621.81
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$562.34
Median
$660.69
Typical High
$831.76
United
Setting
Professional
Modifier
None
Typical Low
$234.42
Median
$275.42
Typical High
$489.78
Wellpoint
Setting
Professional
Modifier
None
Typical Low
$446.68
Median
$446.68
Typical High
$446.68
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$204.17
Median
$208.93
Typical High
$213.80
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$83.18
Median
$83.18
Typical High
$85.11

Where Maryland sits

The same service costs 4.6 times more in Kansas than in Oklahoma. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Maryland· 45th of 51

$447

KS $1,514OK $331

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.