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Cystic Fibrosis Gene Test, Common Changes

Indiana rates for HCPCS 81220

This is a genetic test that checks for the most common changes in the gene linked to cystic fibrosis, an inherited condition that affects the lungs and digestive system. It is often used for carrier screening during family planning or pregnancy, as well as to help confirm a diagnosis.

Rates data updated October 2026.

How much does Cystic Fibrosis Gene Test, Common Changes cost?

$457

Typical negotiated rate. In Indiana, October 2026.

Insurers have agreed to pay about $457 for this service. The price depends on where it is billed: about $347 from a physician practice, and about $562 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$347$224 to $562
FacilityA hospital or hospital-owned outpatient department$562$562 to $1,122

How much rates vary

Facilitymedian $562 · 10th to 90th $447 to $1,660Professionalmedian $347 · 10th to 90th $224 to $832
$200$500$1K$2Kfacility $562professional $347

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$457.09
Median
$691.83
Typical High
$2,041.74
Aetna
Setting
Professional
Modifier
None
Typical Low
$436.52
Median
$457.09
Typical High
$831.76
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$436.52
Median
$562.34
Typical High
$1,659.59
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$223.87
Median
$223.87
Typical High
$831.76
CareSource
Setting
Professional
Modifier
None
Typical Low
$562.34
Median
$616.60
Typical High
$776.25
Cigna
Setting
Facility
Modifier
None
Typical Low
$363.08
Median
$562.34
Typical High
$1,584.89
Cigna
Setting
Professional
Modifier
None
Typical Low
$295.12
Median
$501.19
Typical High
$1,071.52
Physicians Health Plan of Northern Indiana
Setting
Facility
Modifier
None
Typical Low
$912.01
Median
$954.99
Typical High
$2,187.76
Physicians Health Plan of Northern Indiana
Setting
Professional
Modifier
None
Typical Low
$363.08
Median
$467.74
Typical High
$891.25
United
Setting
Professional
Modifier
None
Typical Low
$234.42
Median
$331.13
Typical High
$660.69
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$218.78
Median
$229.09
Typical High
$416.87
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$87.10
Median
$91.20
Typical High
$165.96

Where Indiana sits

The same service costs 4.6 times more in Kansas than in Oklahoma. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Indiana· 42nd of 51

$457

KS $1,514OK $331

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.