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BRAF Gene Change Test

Pennsylvania rates for HCPCS 81210

A laboratory test on a tumor sample or a blood sample that looks for a specific change in the BRAF gene at the spot where it most often goes wrong. This change drives some melanomas, thyroid cancers and bowel cancers, and finding it opens the door to drugs aimed directly at it.

Rates data updated October 2026.

How much does BRAF Gene Change Test cost?

$148

Typical negotiated rate. In Pennsylvania, October 2026.

Insurers have agreed to pay about $148 for this service. The price depends on where it is billed: about $141 from a physician practice, and about $263 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 11 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$141$138 to $174
FacilityA hospital or hospital-owned outpatient department$263$174 to $398

How much rates vary

Facilitymedian $263 · 10th to 90th $141 to $603Professionalmedian $141 · 10th to 90th $89 to $269
$100$200$500$1K$2K$5Kfacility $263professional $141

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$141.25
Median
$147.91
Typical High
$512.86
Aetna
Setting
Professional
Modifier
None
Typical Low
$128.82
Median
$141.25
Typical High
$147.91
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$69.18
Median
$70.79
Typical High
$74.13
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$27.54
Median
$28.18
Typical High
$29.51
AmeriHealth
Setting
Facility
Modifier
None
Typical Low
$147.91
Median
$302.00
Typical High
$1,047.13
Capital Blue Cross
Setting
Facility
Modifier
None
Typical Low
$4,265.80
Median
$5,011.87
Typical High
$79,432.82
Capital Blue Cross
Setting
Professional
Modifier
None
Typical Low
$123.03
Median
$138.04
Typical High
$436.52
Cigna
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$288.40
Typical High
$524.81
Cigna
Setting
Professional
Modifier
None
Typical Low
$83.18
Median
$186.21
Typical High
$269.15
Emblem Health
Setting
Professional
Modifier
None
Typical Low
$104.71
Median
$229.09
Typical High
$229.09
Geisinger
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$173.78
Typical High
$173.78
Geisinger
Setting
Professional
Modifier
None
Typical Low
$173.78
Median
$263.03
Typical High
$446.68
Highmark BCBS
Setting
Facility
Modifier
None
Typical Low
$257.04
Median
$371.54
Typical High
$691.83
Independence Blue Cross
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$288.40
Typical High
$602.56
Martin's Point
Setting
Facility
Modifier
None
Typical Low
$141.25
Median
$141.25
Typical High
$602.56
Martin's Point
Setting
Professional
Modifier
None
Typical Low
$138.04
Median
$141.25
Typical High
$147.91
Martin's Point
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$69.18
Median
$70.79
Typical High
$74.13
Martin's Point
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$27.54
Median
$28.18
Typical High
$29.51
UPMC Health Plan
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$398.11
Typical High
$588.84
UPMC Health Plan
Setting
Professional
Modifier
None
Typical Low
$173.78
Median
$239.88
Typical High
$239.88
United
Setting
Facility
Modifier
None
Typical Low
$158.49
Median
$173.78
Typical High
$208.93
United
Setting
Professional
Modifier
None
Typical Low
$74.13
Median
$104.71
Typical High
$213.80

Where Pennsylvania sits

The same service costs 3.8 times more in Alaska than in Connecticut. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Pennsylvania· 34th of 51

$148

AK $398CT $105

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.