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BRAF Gene Change Test

Illinois rates for HCPCS 81210

A laboratory test on a tumor sample or a blood sample that looks for a specific change in the BRAF gene at the spot where it most often goes wrong. This change drives some melanomas, thyroid cancers and bowel cancers, and finding it opens the door to drugs aimed directly at it.

Rates data updated October 2026.

How much does BRAF Gene Change Test cost?

$135

Typical negotiated rate. In Illinois, October 2026.

Insurers have agreed to pay about $135 for this service. The price depends on where it is billed: about $120 from a physician practice, and about $324 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$120$3.98 to $135
FacilityA hospital or hospital-owned outpatient department$324$234 to $617

How much rates vary

Facilitymedian $324 · 10th to 90th $186 to $1,122Professionalmedian $120 · 10th to 90th $3 to $209
$5$20$100$500$2Kfacility $324professional $120

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$144.54
Median
$275.42
Typical High
$524.81
Aetna
Setting
Professional
Modifier
None
Typical Low
$97.72
Median
$144.54
Typical High
$158.49
BCBS Illinois
Setting
Facility
Modifier
None
Typical Low
$208.93
Median
$309.03
Typical High
$2,187.76
BCBS Illinois
Setting
Professional
Modifier
None
Typical Low
$3.47
Median
$120.23
Typical High
$134.90
Cigna
Setting
Facility
Modifier
None
Typical Low
$194.98
Median
$363.08
Typical High
$724.44
Cigna
Setting
Professional
Modifier
None
Typical Low
$89.13
Median
$213.80
Typical High
$288.40
Hally Health
Setting
Professional
Modifier
None
Typical Low
$177.83
Median
$263.03
Typical High
$426.58
Hally Health
Setting
Facility
Modifier
None
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Hally Health
Setting
Professional
Modifier
None
Typical Low
$229.09
Median
$229.09
Typical High
$229.09
United
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$208.93
Typical High
$218.78
United
Setting
Professional
Modifier
None
Typical Low
$74.13
Median
$104.71
Typical High
$177.83
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$72.44
Median
$125.89
Typical High
$263.03
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$28.84
Median
$51.29
Typical High
$107.15
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$70.79
Median
$72.44
Typical High
$79.43
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$28.18
Median
$28.84
Typical High
$31.62

Where Illinois sits

The same service costs 3.8 times more in Alaska than in Connecticut. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Illinois· 41st of 51

$135

AK $398CT $105

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.