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Maple Syrup Urine Disease Gene Test

South Dakota rates for HCPCS 81205

A genetic test that looks for the common inherited changes in a gene needed to break down certain protein building blocks. Faults in it cause maple syrup urine disease, in which those building blocks build up and can make a baby seriously ill within days of birth; the name comes from the sweet smell of the urine. Only the frequently seen changes are checked, not the whole gene.

Rates data updated July 2026.

How much does Maple Syrup Urine Disease Gene Test cost?

$158

Typical negotiated rate. In South Dakota, July 2026.

Insurers have agreed to pay about $158 for this service. The price depends on where it is billed: about $126 from a physician practice, and about $182 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$126$74.13 to $224
FacilityA hospital or hospital-owned outpatient department$182$182 to $182

How much rates vary

Facilitymedian $182 · 10th to 90th $107 to $182Professionalmedian $126 · 10th to 90th $63 to $229
$50$100$200$500facility $182professional $126

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$66.07
Median
$107.15
Typical High
$107.15
Aetna
Setting
Professional
Modifier
Global
Typical Low
$63.10
Median
$74.13
Typical High
$89.13
Cigna
Setting
Facility
Modifier
Global
Typical Low
$181.97
Median
$181.97
Typical High
$181.97
Cigna
Setting
Professional
Modifier
Global
Typical Low
$138.04
Median
$181.97
Typical High
$229.09
Medica
Setting
Facility
Modifier
Global
Typical Low
$89.13
Median
$107.15
Typical High
$549.54
Medica
Setting
Professional
Modifier
Global
Typical Low
$48.98
Median
$48.98
Typical High
$478.63
Sanford Health Plan
Setting
Professional
Modifier
Global
Typical Low
$134.90
Median
$223.87
Typical High
$263.03
United
Setting
Professional
Modifier
Global
Typical Low
$39.81
Median
$57.54
Typical High
$125.89
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$95.50
Median
$95.50
Typical High
$95.50

Where South Dakota sits

The same service costs 3.0 times more in Alaska than in Washington, DC. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Dakota· 2nd of 51

$158

AK $214DC $70.79

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.