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Definitive Test For A Substance Without Its Own Test

Missouri rates for HCPCS 80377

A laboratory test that confirms and measures a specific drug or substance in a sample when that substance has no standard named test of its own. The laboratory identifies exactly what is present and how much, rather than simply flagging that something from a broad group may be there.

Rates data updated July 2026.

How much does Definitive Test For A Substance Without Its Own Test cost?

$12.30

Typical negotiated rate. In Missouri, July 2026.

Insurers have agreed to pay about $12.30 for this service. The price depends on where it is billed: about $13.18 from a physician practice, and about $0.02 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$13.18$8.71 to $22.39
FacilityA hospital or hospital-owned outpatient department$0.02$0.02 to $0.04

How much rates vary

Facilitymedian $0 · 10th to 90th $0 to $48Professionalmedian $13 · 10th to 90th $3 to $43
$0.1$1.0$10.0$100.0facility $0professional $13

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$0.02
Median
$0.02
Typical High
$0.04
Aetna
Setting
Professional
Modifier
Global
Typical Low
$0.04
Median
$0.04
Typical High
$0.04
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$3.16
Median
$12.30
Typical High
$45.71
BCBS
Setting
Facility
Modifier
Global
Typical Low
$0.03
Median
$0.03
Typical High
$0.03
Cigna
Setting
Professional
Modifier
Global
Typical Low
$10.23
Median
$22.91
Typical High
$37.15
Medica
Setting
Facility
Modifier
Global
Typical Low
$26.30
Median
$112.20
Typical High
$112.20
Medica
Setting
Professional
Modifier
Global
Typical Low
$10.00
Median
$13.80
Typical High
$25.12
United
Setting
Facility
Modifier
Global
Typical Low
$10.47
Median
$14.45
Typical High
$24.55
United
Setting
Professional
Modifier
Global
Typical Low
$10.00
Median
$13.80
Typical High
$27.54

Where Missouri sits

The same service costs 2691.5 times more in Alaska than in Pennsylvania. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Missouri $12.30 · 32nd of 51
AK $81.28PA $0.03

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.