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Definitive Test for Buprenorphine

Nationwide rates for HCPCS 80348

A laboratory test that confirms whether buprenorphine — a medicine used to treat opioid dependence and, in some forms, pain — and its breakdown products are present in a sample, and can measure how much. Unlike a rapid screening cup, it identifies the specific substance rather than flagging a broad group. Results are used to check that a prescribed medicine is being taken as intended or to look into an unexpected screening result.

Rates data updated July 2026.

Facilitymedian $0 · 10th–90th $0$490%10%20%10th90th$0Professionalmedian $16 · 10th–90th $6$350%20%10th90th$16$0.0$0.5$10.0$200.0$5.0K$100.0K$2.0M

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$0.02
Median
$0.03
Typical High
$0.08
Aetna
Setting
Professional
Modifier
Global
Typical Low
$0.02
Median
$0.03
Typical High
$12.30
BCBS
Setting
Facility
Modifier
Global
Typical Low
$6.46
Median
$12.88
Typical High
$25.70
BCBS
Setting
Professional
Modifier
Global
Typical Low
$6.46
Median
$6.46
Typical High
$26.92
Cigna
Setting
Facility
Modifier
Global
Typical Low
$28.18
Median
$43.65
Typical High
$138.04
Cigna
Setting
Professional
Modifier
Global
Typical Low
$16.98
Median
$21.38
Typical High
$35.48
United
Setting
Facility
Modifier
Global
Typical Low
$6.76
Median
$14.45
Typical High
$19.50
United
Setting
Professional
Modifier
Global
Typical Low
$15.14
Median
$22.91
Typical High
$70.79