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Lab Test For Serotonin-Type Antidepressants

Massachusetts rates for HCPCS 80333

A laboratory test that identifies and measures specific antidepressant medicines of the serotonin-acting class in a blood or urine sample. It uses precise chemical analysis to name the individual drug present and how much of it there is, rather than giving a simple positive or negative screen. Several drugs of the class are covered by the single test.

Rates data updated October 2026.

How much does Lab Test For Serotonin-Type Antidepressants cost?

$26.92

Typical negotiated rate. In Massachusetts, October 2026.

Insurers have agreed to pay about $26.92 for this service. The price depends on where it is billed: about $21.88 from a physician practice, and about $50.12 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$21.88$14.79 to $31.62
FacilityA hospital or hospital-owned outpatient department$50.12$18.62 to $3,090

How much rates vary

Facilitymedian $50 · 10th to 90th $15 to $4,898Professionalmedian $22 · 10th to 90th $15 to $62
$0.1$1$10$100$1K$10Kfacility $50professional $22

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$0.02
Median
$0.02
Typical High
$0.04
Aetna
Setting
Professional
Modifier
None
Typical Low
$77.62
Median
$77.62
Typical High
$77.62
AllWays Health Partners
Setting
Facility
Modifier
None
Typical Low
$50.12
Median
$50.12
Typical High
$50.12
BCBS Massachusetts
Setting
Facility
Modifier
None
Typical Low
$14.79
Median
$18.62
Typical High
$37.15
BCBS Massachusetts
Setting
Professional
Modifier
None
Typical Low
$21.88
Median
$21.88
Typical High
$21.88
Cigna
Setting
Professional
Modifier
None
Typical Low
$23.99
Median
$23.99
Typical High
$30.20
Fallon Health
Setting
Facility
Modifier
None
Typical Low
$83.18
Median
$3,630.78
Typical High
$9,772.37
Harvard Pilgrim
Setting
Professional
Modifier
None
Typical Low
$14.79
Median
$21.38
Typical High
$61.66
Mass General Brigham
Setting
Facility
Modifier
None
Typical Low
$50.12
Median
$50.12
Typical High
$50.12
Well Sense
Setting
Facility
Modifier
None
Typical Low
$2,511.89
Median
$3,090.30
Typical High
$4,897.79
Well Sense
Setting
Professional
Modifier
None
Typical Low
$2,511.89
Median
$2,511.89
Typical High
$3,019.95

Where Massachusetts sits

The same service costs 5128.6 times more in Kansas than in Tennessee. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 17th of 51

$26.92

KS $102TN $0.02

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.