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Lab Test For Serotonin-Type Antidepressants

California rates for HCPCS 80333

A laboratory test that identifies and measures specific antidepressant medicines of the serotonin-acting class in a blood or urine sample. It uses precise chemical analysis to name the individual drug present and how much of it there is, rather than giving a simple positive or negative screen. Several drugs of the class are covered by the single test.

Rates data updated October 2026.

How much does Lab Test For Serotonin-Type Antidepressants cost?

$26.92

Typical negotiated rate. In California, October 2026.

Insurers have agreed to pay about $26.92 for this service. The price depends on where it is billed: about $26.92 from a physician practice, and about $0.06 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 9 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$26.92$5.89 to $38.02
FacilityA hospital or hospital-owned outpatient department$0.06$0.04 to $6.17

How much rates vary

Facilitymedian $0 · 10th to 90th $0 to $21Professionalmedian $27 · 10th to 90th $6 to $50
$0.1$1$10$100$1Kfacility $0professional $27

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$0.02
Median
$0.05
Typical High
$0.07
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$0.02
Median
$0.04
Typical High
$0.07
Ambetter
Setting
Professional
Modifier
None (both parts)
Typical Low
$14.13
Median
$14.13
Typical High
$14.79
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$5.89
Median
$6.31
Typical High
$6.92
Anthem BCBS
Setting
Professional
Modifier
None (both parts)
Typical Low
$5.89
Median
$5.89
Typical High
$44.67
Blue Shield
Setting
Professional
Modifier
None (both parts)
Typical Low
$26.92
Median
$38.02
Typical High
$52.48
Cigna
Setting
Facility
Modifier
None
Typical Low
$5,623.41
Median
$5,623.41
Typical High
$6,165.95
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$23.99
Median
$23.99
Typical High
$30.20
Contra Costa Health
Setting
Professional
Modifier
None
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$15.85
Median
$45.71
Typical High
$407.38
Providence
Setting
Facility
Modifier
None
Typical Low
$20.89
Median
$36.31
Typical High
$6,165.95
Providence
Setting
Professional
Modifier
None (both parts)
Typical Low
$79.43
Median
$79.43
Typical High
$79.43
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$22.91
Median
$22.91
Typical High
$22.91
3 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$0.02
Median
$0.03
Typical High
$0.04
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$5.01
Median
$5.01
Typical High
$5.01
Providence
Setting
Professional
Modifier
26 · Professional part
Typical Low
$5.01
Median
$5.01
Typical High
$5.01

Where California sits

The same service costs 5128.6 times more in Kansas than in Tennessee. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

California· 16th of 51

$26.92

KS $102TN $0.02

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.