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Chemodenervation Injections For Chronic Migraine

Missouri rates for HCPCS 64615

An injectable muscle-relaxing medication is given as a series of small injections across muscles of the head and neck on both sides, a treatment protocol used for people with chronic migraine. It is typically repeated roughly every three months.

Rates data updated October 2026.

How much does Chemodenervation Injections For Chronic Migraine cost?

$166

Typical negotiated rate. In Missouri, October 2026.

Insurers have agreed to pay about $166 for this service. The price depends on where it is billed: about $158 from a physician practice, and about $646 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$158$135 to $229
FacilityA hospital or hospital-owned outpatient department$646$155 to $1,698

How much rates vary

Facilitymedian $646 · 10th to 90th $98 to $3,715Professionalmedian $158 · 10th to 90th $117 to $871
$100$200$500$1K$2K$5Kfacility $646professional $158

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$128.82
Median
$2,754.23
Typical High
$6,309.57
Aetna
Setting
Professional
Modifier
None
Typical Low
$102.33
Median
$128.82
Typical High
$223.87
Ambetter
Setting
Professional
Modifier
None
Typical Low
$128.82
Median
$165.96
Typical High
$208.93
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$151.36
Median
$1,621.81
Typical High
$3,890.45
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$114.82
Median
$134.90
Typical High
$213.80
BCBS Kansas City
Setting
Professional
Modifier
None
Typical Low
$114.82
Median
$154.88
Typical High
$194.98
Cigna
Setting
Facility
Modifier
None
Typical Low
$66.07
Median
$87.10
Typical High
$562.34
Cigna
Setting
Professional
Modifier
None
Typical Low
$120.23
Median
$158.49
Typical High
$275.42
Medica
Setting
Facility
Modifier
None
Typical Low
$54.95
Median
$295.12
Typical High
$1,071.52
Medica
Setting
Professional
Modifier
None
Typical Low
$177.83
Median
$870.96
Typical High
$1,096.48
United
Setting
Facility
Modifier
None
Typical Low
$123.03
Median
$602.56
Typical High
$2,137.96
United
Setting
Professional
Modifier
None
Typical Low
$117.49
Median
$213.80
Typical High
$295.12
6 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$51.29
Median
$64.57
Typical High
$79.43
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$20.42
Median
$25.70
Typical High
$31.62
Aetna
Setting
Professional
Modifier
54 · Surgery only
Typical Low
$77.62
Median
$95.50
Typical High
$117.49
Aetna
Setting
Professional
Modifier
55 · Aftercare only
Typical Low
$15.49
Median
$19.50
Typical High
$23.99
Aetna
Setting
Professional
Modifier
56 · Pre-op care only
Typical Low
$10.23
Median
$12.88
Typical High
$15.85
Aetna
Setting
Professional
Modifier
78 · Unplanned return to OR
Typical Low
$72.44
Median
$89.13
Typical High
$109.65

Where Missouri sits

The same service costs 3.9 times more in Alaska than in Florida. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 36th of 51

$166

AK $501FL $129

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.