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Blood Exchange Transfusion, Non-Newborn

Massachusetts rates for HCPCS 36455

This procedure gradually removes a patient's blood while simultaneously replacing it with donor blood, diluting out harmful substances such as toxins, abnormal blood cells, or excess bilirubin. It is performed in older infants, children, or adults for conditions like severe sickle cell complications or certain poisonings. The exchange is done gradually to keep the patient's blood volume and pressure stable throughout.

Rates data updated July 2026.

Facilitymedian $1,905 · 10th–90th $120$3,7150%5%10%10th90th$1,905Professionalmedian $158 · 10th–90th $117$3310%10%10th90th$158$100.0$500.0$2.0K$10.0K$50.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$1,000.00
Median
$2,238.72
Typical High
$3,715.35
Aetna
Setting
Professional
Modifier
Global
Typical Low
$104.71
Median
$141.25
Typical High
$251.19
AllWays Health Partners
Setting
Facility
Modifier
Global
Typical Low
$56.23
Median
$912.01
Typical High
$2,818.38
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$117.49
Median
$190.55
Typical High
$1,778.28
Cigna
Setting
Professional
Modifier
Global
Typical Low
$120.23
Median
$190.55
Typical High
$346.74
Fallon Health
Setting
Facility
Modifier
Global
Typical Low
$100.00
Median
$154.88
Typical High
$1,174.90
Fallon Health
Setting
Professional
Modifier
Global
Typical Low
$100.00
Median
$151.36
Typical High
$229.09
Harvard Pilgrim
Setting
Facility
Modifier
Global
Typical Low
$741.31
Median
$2,041.74
Typical High
$3,467.37
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$120.23
Median
$208.93
Typical High
$323.59
Mass General Brigham
Setting
Facility
Modifier
Global
Typical Low
$56.23
Median
$912.01
Typical High
$2,818.38
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$117.49
Median
$190.55
Typical High
$1,778.28
United
Setting
Facility
Modifier
Global
Typical Low
$616.60
Median
$1,737.80
Typical High
$2,754.23
United
Setting
Professional
Modifier
Global
Typical Low
$131.83
Median
$213.80
Typical High
$354.81