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27-Gene Medication Response Test With Drug Interactions

South Carolina rates for HCPCS 0349U

Helps a clinician choose medications and doses that suit your genetics. Twenty-seven genes that affect how the body handles medicines are examined in either whole blood or a cheek (buccal) swab, and each gene is reported as a metabolizer type. This version also reports how specific medications interact with those gene results.

Rates data updated July 2026.

How much does 27-Gene Medication Response Test With Drug Interactions cost?

$589

Typical negotiated rate. In South Carolina, July 2026.

Insurers have agreed to pay about $589 for this service. The price depends on where it is billed: about $589 from a physician practice, and about $1,820 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$589$575 to $603
FacilityA hospital or hospital-owned outpatient department$1,820$631 to $2,399

How much rates vary

Facilitymedian $1,820 · 10th to 90th $562 to $3,548Professionalmedian $589 · 10th to 90th $447 to $741
$500$1K$2Kfacility $1,820professional $589

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$575.44
Median
$1,819.70
Typical High
$3,548.13
Aetna
Setting
Professional
Modifier
Global
Typical Low
$575.44
Median
$588.84
Typical High
$645.65
BCBS
Setting
Professional
Modifier
Global
Typical Low
$741.31
Median
$794.33
Typical High
$1,122.02
Cigna
Setting
Facility
Modifier
Global
Typical Low
$501.19
Median
$1,862.09
Typical High
$4,265.80
Medcost
Setting
Facility
Modifier
Global
Typical Low
$446.68
Median
$630.96
Typical High
$954.99
United
Setting
Facility
Modifier
Global
Typical Low
$660.69
Median
$741.31
Typical High
$741.31
United
Setting
Professional
Modifier
Global
Typical Low
$309.03
Median
$446.68
Typical High
$741.31

Where South Carolina sits

The same service costs 3.7 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Carolina· 38th of 51

$589

AK $1,660WY $447

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.