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27-Gene Medication Response Test With Drug Interactions

Pennsylvania rates for HCPCS 0349U

Helps a clinician choose medications and doses that suit your genetics. Twenty-seven genes that affect how the body handles medicines are examined in either whole blood or a cheek (buccal) swab, and each gene is reported as a metabolizer type. This version also reports how specific medications interact with those gene results.

Rates data updated July 2026.

How much does 27-Gene Medication Response Test With Drug Interactions cost?

$631

Typical negotiated rate. In Pennsylvania, July 2026.

Insurers have agreed to pay about $631 for this service. The price depends on where it is billed: about $603 from a physician practice, and about $1,445 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$603$447 to $631
FacilityA hospital or hospital-owned outpatient department$1,445$955 to $1,905

How much rates vary

Facilitymedian $1,445 · 10th to 90th $631 to $2,630Professionalmedian $603 · 10th to 90th $407 to $741
$500$1K$2Kfacility $1,445professional $603

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$630.96
Median
$1,445.44
Typical High
$2,630.27
Aetna
Setting
Professional
Modifier
Global
Typical Low
$407.38
Median
$602.56
Typical High
$691.83
Capital Blue Cross
Setting
Professional
Modifier
Global
Typical Low
$575.44
Median
$575.44
Typical High
$575.44
Cigna
Setting
Facility
Modifier
Global
Typical Low
$537.03
Median
$1,023.29
Typical High
$2,511.89
Cigna
Setting
Professional
Modifier
Global
Typical Low
$3,548.13
Median
$3,548.13
Typical High
$3,548.13
Emblem Health
Setting
Professional
Modifier
Global
Typical Low
$977.24
Median
$977.24
Typical High
$1,071.52
Geisinger
Setting
Facility
Modifier
Global
Typical Low
$741.31
Median
$741.31
Typical High
$741.31
Geisinger
Setting
Professional
Modifier
Global
Typical Low
$562.34
Median
$851.14
Typical High
$1,412.54
Martin's Point
Setting
Facility
Modifier
Global
Typical Low
$870.96
Median
$1,548.82
Typical High
$2,630.27
Martin's Point
Setting
Professional
Modifier
Global
Typical Low
$407.38
Median
$602.56
Typical High
$2,187.76
United
Setting
Facility
Modifier
Global
Typical Low
$446.68
Median
$446.68
Typical High
$446.68
United
Setting
Professional
Modifier
Global
Typical Low
$309.03
Median
$446.68
Typical High
$1,000.00

Where Pennsylvania sits

The same service costs 3.7 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Pennsylvania· 34th of 51

$631

AK $1,660WY $447

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.