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27-Gene Medication Response Test With Drug Interactions

Nebraska rates for HCPCS 0349U

Helps a clinician choose medications and doses that suit your genetics. Twenty-seven genes that affect how the body handles medicines are examined in either whole blood or a cheek (buccal) swab, and each gene is reported as a metabolizer type. This version also reports how specific medications interact with those gene results.

Rates data updated July 2026.

How much does 27-Gene Medication Response Test With Drug Interactions cost?

$741

Typical negotiated rate. In Nebraska, July 2026.

Insurers have agreed to pay about $741 for this service. The price depends on where it is billed: about $490 from a physician practice, and about $1,202 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$490$447 to $1,148
FacilityA hospital or hospital-owned outpatient department$1,202$741 to $1,950

How much rates vary

Facilitymedian $1,202 · 10th to 90th $525 to $2,239Professionalmedian $490 · 10th to 90th $447 to $1,778
$500$1K$2Kfacility $1,202professional $490

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$524.81
Median
$1,949.84
Typical High
$3,715.35
Aetna
Setting
Professional
Modifier
Global
Typical Low
$489.78
Median
$489.78
Typical High
$1,778.28
BCBS
Setting
Facility
Modifier
Global
Typical Low
$891.25
Median
$1,148.15
Typical High
$2,238.72
BCBS
Setting
Professional
Modifier
Global
Typical Low
$1,071.52
Median
$1,148.15
Typical High
$1,230.27
Cigna
Setting
Professional
Modifier
Global
Typical Low
$891.25
Median
$1,412.54
Typical High
$1,778.28
Medica
Setting
Facility
Modifier
Global
Typical Low
$489.78
Median
$1,122.02
Typical High
$3,548.13
Medica
Setting
Professional
Modifier
Global
Typical Low
$309.03
Median
$446.68
Typical High
$2,137.96
Midlands
Setting
Professional
Modifier
Global
Typical Low
$891.25
Median
$891.25
Typical High
$891.25
United
Setting
Facility
Modifier
Global
Typical Low
$446.68
Median
$741.31
Typical High
$891.25
United
Setting
Professional
Modifier
Global
Typical Low
$426.58
Median
$446.68
Typical High
$2,041.74

Where Nebraska sits

The same service costs 3.7 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Nebraska· 20th of 51

$741

AK $1,660WY $447

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.