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27-Gene Medication Response Test With Drug Interactions

Missouri rates for HCPCS 0349U

Helps a clinician choose medications and doses that suit your genetics. Twenty-seven genes that affect how the body handles medicines are examined in either whole blood or a cheek (buccal) swab, and each gene is reported as a metabolizer type. This version also reports how specific medications interact with those gene results.

Rates data updated July 2026.

How much does 27-Gene Medication Response Test With Drug Interactions cost?

$776

Typical negotiated rate. In Missouri, July 2026.

Insurers have agreed to pay about $776 for this service. The price depends on where it is billed: about $692 from a physician practice, and about $1,259 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$692$692 to $851
FacilityA hospital or hospital-owned outpatient department$1,259$891 to $1,288

How much rates vary

Facilitymedian $1,259 · 10th to 90th $724 to $1,445Professionalmedian $692 · 10th to 90th $447 to $1,288
$500$1K$2Kfacility $1,259professional $692

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$724.44
Median
$1,288.25
Typical High
$1,445.44
Aetna
Setting
Professional
Modifier
Global
Typical Low
$724.44
Median
$724.44
Typical High
$2,570.40
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$691.83
Median
$691.83
Typical High
$1,230.27
Cigna
Setting
Facility
Modifier
Global
Typical Low
$1,047.13
Median
$1,548.82
Typical High
$3,801.89
Medica
Setting
Facility
Modifier
Global
Typical Low
$630.96
Median
$891.25
Typical High
$3,548.13
Medica
Setting
Professional
Modifier
Global
Typical Low
$309.03
Median
$446.68
Typical High
$3,715.35
United
Setting
Facility
Modifier
Global
Typical Low
$269.15
Median
$741.31
Typical High
$891.25
United
Setting
Professional
Modifier
Global
Typical Low
$309.03
Median
$446.68
Typical High
$870.96

Where Missouri sits

The same service costs 3.7 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 12th of 51

$776

AK $1,660WY $447

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.