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27-Gene Medication Response Test With Drug Interactions

Massachusetts rates for HCPCS 0349U

Helps a clinician choose medications and doses that suit your genetics. Twenty-seven genes that affect how the body handles medicines are examined in either whole blood or a cheek (buccal) swab, and each gene is reported as a metabolizer type. This version also reports how specific medications interact with those gene results.

Rates data updated July 2026.

How much does 27-Gene Medication Response Test With Drug Interactions cost?

$741

Typical negotiated rate. In Massachusetts, July 2026.

Insurers have agreed to pay about $741 for this service. The price depends on where it is billed: about $741 from a physician practice, and about $1,698 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$741$562 to $741
FacilityA hospital or hospital-owned outpatient department$1,698$1,023 to $2,188

How much rates vary

Facilitymedian $1,698 · 10th to 90th $525 to $2,570Professionalmedian $741 · 10th to 90th $447 to $1,413
$500$1K$2K$5Kfacility $1,698professional $741

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$524.81
Median
$1,659.59
Typical High
$2,398.83
Aetna
Setting
Professional
Modifier
Global
Typical Low
$407.38
Median
$524.81
Typical High
$602.56
AllWays Health Partners
Setting
Facility
Modifier
Global
Typical Low
$812.83
Median
$1,995.26
Typical High
$3,548.13
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$446.68
Median
$741.31
Typical High
$2,454.71
Cigna
Setting
Facility
Modifier
Global
Typical Low
$501.19
Median
$575.44
Typical High
$1,202.26
Cigna
Setting
Professional
Modifier
Global
Typical Low
$912.01
Median
$912.01
Typical High
$1,122.02
Fallon Health
Setting
Facility
Modifier
Global
Typical Low
$83.18
Median
$4,897.79
Typical High
$9,772.37
Fallon Health
Setting
Professional
Modifier
Global
Typical Low
$1,071.52
Median
$1,071.52
Typical High
$1,258.93
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$741.31
Median
$741.31
Typical High
$1,230.27
Mass General Brigham
Setting
Facility
Modifier
Global
Typical Low
$812.83
Median
$1,995.26
Typical High
$3,548.13
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$446.68
Median
$741.31
Typical High
$2,454.71
United
Setting
Facility
Modifier
Global
Typical Low
$446.68
Median
$660.69
Typical High
$891.25
United
Setting
Professional
Modifier
Global
Typical Low
$446.68
Median
$741.31
Typical High
$1,698.24

Where Massachusetts sits

The same service costs 3.7 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 13th of 51

$741

AK $1,660WY $447

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.