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27-Gene Medication Response Test With Drug Interactions

Florida rates for HCPCS 0349U

Helps a clinician choose medications and doses that suit your genetics. Twenty-seven genes that affect how the body handles medicines are examined in either whole blood or a cheek (buccal) swab, and each gene is reported as a metabolizer type. This version also reports how specific medications interact with those gene results.

Rates data updated July 2026.

How much does 27-Gene Medication Response Test With Drug Interactions cost?

$537

Typical negotiated rate. In Florida, July 2026.

Insurers have agreed to pay about $537 for this service. The price depends on where it is billed: about $525 from a physician practice, and about $1,380 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$525$447 to $603
FacilityA hospital or hospital-owned outpatient department$1,380$661 to $2,138

How much rates vary

Facilitymedian $1,380 · 10th to 90th $537 to $3,981Professionalmedian $525 · 10th to 90th $389 to $676
$200$500$1K$2Kfacility $1,380professional $525

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$537.03
Median
$1,778.28
Typical High
$3,981.07
Aetna
Setting
Professional
Modifier
Global
Typical Low
$446.68
Median
$524.81
Typical High
$645.65
AvMed
Setting
Professional
Modifier
Global
Typical Low
$588.84
Median
$741.31
Typical High
$741.31
Cigna
Setting
Facility
Modifier
Global
Typical Low
$380.19
Median
$562.34
Typical High
$3,019.95
Cigna
Setting
Professional
Modifier
Global
Typical Low
$912.01
Median
$1,071.52
Typical High
$3,548.13
Florida Blue
Setting
Facility
Modifier
Global
Typical Low
$1,380.38
Median
$1,380.38
Typical High
$1,380.38
Florida Blue
Setting
Professional
Modifier
Global
Typical Low
$446.68
Median
$446.68
Typical High
$630.96
Molina
Setting
Professional
Modifier
Global
Typical Low
$50.12
Median
$446.68
Typical High
$741.31
United
Setting
Facility
Modifier
Global
Typical Low
$309.03
Median
$660.69
Typical High
$912.01
United
Setting
Professional
Modifier
Global
Typical Low
$257.04
Median
$316.23
Typical High
$977.24
Wellpoint
Setting
Professional
Modifier
Global
Typical Low
$446.68
Median
$446.68
Typical High
$741.31

Where Florida sits

The same service costs 3.7 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Florida· 47th of 51

$537

AK $1,660WY $447

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.