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Urine Two-Gene Prostate Cancer Risk Test

Pennsylvania rates for HCPCS 0339U

Helps judge whether a man is likely to have prostate cancer serious enough to need a biopsy. The activity of two genes, HOXC6 and DLX1, is measured in a urine sample collected straight after a digital rectal examination, and the result is reported as a probability.

Rates data updated October 2026.

How much does Urine Two-Gene Prostate Cancer Risk Test cost?

$589

Typical negotiated rate. In Pennsylvania, October 2026.

Insurers have agreed to pay about $589 for this service. The price depends on where it is billed: about $589 from a physician practice, and about $912 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$589$537 to $646
FacilityA hospital or hospital-owned outpatient department$912$759 to $1,259

How much rates vary

Facilitymedian $912 · 10th to 90th $646 to $2,188Professionalmedian $589 · 10th to 90th $407 to $813
$500$1K$2Kfacility $912professional $589

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$645.65
Median
$1,071.52
Typical High
$2,570.40
Aetna
Setting
Professional
Modifier
None
Typical Low
$602.56
Median
$616.60
Typical High
$645.65
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$302.00
Median
$309.03
Typical High
$323.59
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$120.23
Median
$123.03
Typical High
$128.82
Capital Blue Cross
Setting
Professional
Modifier
None
Typical Low
$478.63
Median
$588.84
Typical High
$588.84
Cigna
Setting
Facility
Modifier
None
Typical Low
$741.31
Median
$1,047.13
Typical High
$1,737.80
Cigna
Setting
Professional
Modifier
None
Typical Low
$3,630.78
Median
$3,630.78
Typical High
$3,630.78
Emblem Health
Setting
Professional
Modifier
None
Typical Low
$537.03
Median
$1,000.00
Typical High
$1,096.48
Geisinger
Setting
Facility
Modifier
None
Typical Low
$758.58
Median
$758.58
Typical High
$758.58
Geisinger
Setting
Professional
Modifier
None
Typical Low
$575.44
Median
$870.96
Typical High
$1,479.11
Martin's Point
Setting
Facility
Modifier
None
Typical Low
$645.65
Median
$1,479.11
Typical High
$2,691.53
Martin's Point
Setting
Professional
Modifier
None
Typical Low
$602.56
Median
$616.60
Typical High
$645.65
Martin's Point
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$302.00
Median
$309.03
Typical High
$323.59
Martin's Point
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$120.23
Median
$123.03
Typical High
$128.82
United
Setting
Professional
Modifier
None
Typical Low
$316.23
Median
$457.09
Typical High
$912.01

Where Pennsylvania sits

The same service costs 12.0 times more in Texas than in New Mexico. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Pennsylvania· 33rd of 51

$589

TX $3,802NM $316

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.