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Urine Two-Gene Prostate Cancer Risk Test

Massachusetts rates for HCPCS 0339U

Helps judge whether a man is likely to have prostate cancer serious enough to need a biopsy. The activity of two genes, HOXC6 and DLX1, is measured in a urine sample collected straight after a digital rectal examination, and the result is reported as a probability.

Rates data updated July 2026.

How much does Urine Two-Gene Prostate Cancer Risk Test cost?

$759

Typical negotiated rate. In Massachusetts, July 2026.

Insurers have agreed to pay about $759 for this service. The price depends on where it is billed: about $759 from a physician practice, and about $1,738 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$759$575 to $759
FacilityA hospital or hospital-owned outpatient department$1,738$1,047 to $2,239

How much rates vary

Facilitymedian $1,738 · 10th to 90th $537 to $2,630Professionalmedian $759 · 10th to 90th $457 to $1,380
$500$1K$2K$5Kfacility $1,738professional $759

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$537.03
Median
$1,698.24
Typical High
$2,454.71
Aetna
Setting
Professional
Modifier
Global
Typical Low
$416.87
Median
$537.03
Typical High
$616.60
AllWays Health Partners
Setting
Facility
Modifier
Global
Typical Low
$831.76
Median
$2,041.74
Typical High
$3,630.78
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$457.09
Median
$758.58
Typical High
$2,511.89
Cigna
Setting
Facility
Modifier
Global
Typical Low
$512.86
Median
$588.84
Typical High
$1,230.27
Cigna
Setting
Professional
Modifier
Global
Typical Low
$933.25
Median
$933.25
Typical High
$1,148.15
Fallon Health
Setting
Facility
Modifier
Global
Typical Low
$83.18
Median
$4,897.79
Typical High
$9,772.37
Fallon Health
Setting
Professional
Modifier
Global
Typical Low
$1,096.48
Median
$1,096.48
Typical High
$1,288.25
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$758.58
Median
$758.58
Typical High
$1,258.93
Mass General Brigham
Setting
Facility
Modifier
Global
Typical Low
$831.76
Median
$2,041.74
Typical High
$3,630.78
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$457.09
Median
$758.58
Typical High
$2,511.89
United
Setting
Facility
Modifier
Global
Typical Low
$457.09
Median
$691.83
Typical High
$912.01
United
Setting
Professional
Modifier
Global
Typical Low
$457.09
Median
$758.58
Typical High
$1,737.80

Where Massachusetts sits

The same service costs 3.4 times more in Alaska than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 15th of 51

$759

AK $1,698NE $501

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.