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Urine Two-Gene Prostate Cancer Risk Test

Iowa rates for HCPCS 0339U

Helps judge whether a man is likely to have prostate cancer serious enough to need a biopsy. The activity of two genes, HOXC6 and DLX1, is measured in a urine sample collected straight after a digital rectal examination, and the result is reported as a probability.

Rates data updated October 2026.

How much does Urine Two-Gene Prostate Cancer Risk Test cost?

$832

Typical negotiated rate. In Iowa, October 2026.

Insurers have agreed to pay about $832 for this service. Most negotiated rates run $468 to $1,349.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $1,318 · 10th to 90th $851 to $2,239Professionalmedian $759 · 10th to 90th $457 to $2,951
$500$1K$2Kfacility $1,318professional $759

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$588.84
Median
$1,584.89
Typical High
$2,137.96
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$588.84
Median
$588.84
Typical High
$912.01
Cigna
Setting
Facility
Modifier
TC · Technical part
Typical Low
$912.01
Median
$912.01
Typical High
$912.01
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$933.25
Median
$1,000.00
Typical High
$1,819.70
Hally Health
Setting
Professional
Modifier
None
Typical Low
$645.65
Median
$977.24
Typical High
$1,318.26
Medica
Setting
Facility
Modifier
None
Typical Low
$912.01
Median
$1,318.26
Typical High
$2,344.23
Medica
Setting
Professional
Modifier
None (both parts)
Typical Low
$457.09
Median
$912.01
Typical High
$3,801.89
Medica
Setting
Professional
Modifier
TC · Technical part
Typical Low
$3,890.45
Median
$3,890.45
Typical High
$3,890.45
Midlands
Setting
Professional
Modifier
None
Typical Low
$933.25
Median
$933.25
Typical High
$933.25
Midlands
Setting
Facility
Modifier
TC · Technical part
Typical Low
$912.01
Median
$912.01
Typical High
$912.01
Midlands
Setting
Professional
Modifier
None (both parts)
Typical Low
$1,000.00
Median
$1,000.00
Typical High
$1,000.00
Oscar Health
Setting
Professional
Modifier
None (both parts)
Typical Low
$758.58
Median
$831.76
Typical High
$1,621.81
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$457.09
Median
$457.09
Typical High
$1,548.82
Wellmark
Setting
Professional
Modifier
None (both parts)
Typical Low
$758.58
Median
$758.58
Typical High
$758.58
3 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$512.86
Median
$588.84
Typical High
$741.31
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$295.12
Median
$295.12
Typical High
$457.09
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$117.49
Median
$117.49
Typical High
$181.97

Where Iowa sits

The same service costs 12.0 times more in Texas than in New Mexico. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Iowa· 10th of 51

$832

TX $3,802NM $316

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.