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Urine Two-Gene Prostate Cancer Risk Test

Florida rates for HCPCS 0339U

Helps judge whether a man is likely to have prostate cancer serious enough to need a biopsy. The activity of two genes, HOXC6 and DLX1, is measured in a urine sample collected straight after a digital rectal examination, and the result is reported as a probability.

Rates data updated October 2026.

How much does Urine Two-Gene Prostate Cancer Risk Test cost?

$490

Typical negotiated rate. In Florida, October 2026.

Insurers have agreed to pay about $490 for this service. The price depends on where it is billed: about $457 from a physician practice, and about $1,413 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$457$407 to $575
FacilityA hospital or hospital-owned outpatient department$1,413$1,413 to $1,413

How much rates vary

Facilitymedian $1,413 · 10th to 90th $575 to $1,413Professionalmedian $457 · 10th to 90th $316 to $759
$500$1K$2Kfacility $1,413professional $457

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$549.54
Typical High
$1,513.56
Aetna
Setting
Professional
Modifier
None
Typical Low
$457.09
Median
$489.78
Typical High
$616.60
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$229.09
Median
$245.47
Typical High
$309.03
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$91.20
Median
$97.72
Typical High
$123.03
AvMed
Setting
Professional
Modifier
None
Typical Low
$602.56
Median
$758.58
Typical High
$758.58
Cigna
Setting
Facility
Modifier
None
Typical Low
$389.05
Median
$575.44
Typical High
$3,090.30
Cigna
Setting
Professional
Modifier
None
Typical Low
$3,630.78
Median
$3,630.78
Typical High
$3,630.78
Florida Blue
Setting
Facility
Modifier
None
Typical Low
$1,412.54
Median
$1,412.54
Typical High
$1,412.54
Florida Blue
Setting
Professional
Modifier
None
Typical Low
$457.09
Median
$457.09
Typical High
$645.65
Molina
Setting
Professional
Modifier
None
Typical Low
$50.12
Median
$457.09
Typical High
$616.60
United
Setting
Professional
Modifier
None
Typical Low
$263.03
Median
$323.59
Typical High
$1,000.00
Wellpoint
Setting
Professional
Modifier
None
Typical Low
$457.09
Median
$457.09
Typical High
$758.58

Where Florida sits

The same service costs 12.0 times more in Texas than in New Mexico. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Florida· 42nd of 51

$490

TX $3,802NM $316

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.