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Urine Two-Gene Prostate Cancer Risk Test

Colorado rates for HCPCS 0339U

Helps judge whether a man is likely to have prostate cancer serious enough to need a biopsy. The activity of two genes, HOXC6 and DLX1, is measured in a urine sample collected straight after a digital rectal examination, and the result is reported as a probability.

Rates data updated October 2026.

How much does Urine Two-Gene Prostate Cancer Risk Test cost?

$1,047

Typical negotiated rate. In Colorado, October 2026.

Insurers have agreed to pay about $1,047 for this service. The price depends on where it is billed: about $457 from a physician practice, and about $2,188 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$457$316 to $977
FacilityA hospital or hospital-owned outpatient department$2,188$1,514 to $2,630

How much rates vary

Facilitymedian $2,188 · 10th to 90th $589 to $3,467Professionalmedian $457 · 10th to 90th $316 to $1,549
$500$1K$2K$5Kfacility $2,188professional $457

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$758.58
Median
$1,584.89
Typical High
$3,548.13
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$575.44
Median
$575.44
Typical High
$812.83
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$1,000.00
Median
$2,290.87
Typical High
$3,467.37
Anthem BCBS
Setting
Professional
Modifier
None (both parts)
Typical Low
$316.23
Median
$316.23
Typical High
$1,698.24
Cigna
Setting
Facility
Modifier
None
Typical Low
$446.68
Median
$660.69
Typical High
$2,398.83
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$933.25
Median
$1,096.48
Typical High
$1,096.48
Denver HMP
Setting
Facility
Modifier
None
Typical Low
$575.44
Median
$691.83
Typical High
$1,047.13
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$758.58
Median
$1,071.52
Typical High
$1,548.82
Select Health
Setting
Facility
Modifier
None
Typical Low
$758.58
Median
$1,412.54
Typical High
$1,584.89
Select Health
Setting
Professional
Modifier
None (both parts)
Typical Low
$537.03
Median
$758.58
Typical High
$1,148.15
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$316.23
Median
$316.23
Typical High
$562.34
3 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$575.44
Median
$575.44
Typical High
$602.56
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$281.84
Median
$288.40
Typical High
$407.38
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$114.82
Median
$114.82
Typical High
$162.18

Where Colorado sits

The same service costs 12.0 times more in Texas than in New Mexico. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Colorado· 5th of 51

$1,047

TX $3,802NM $316

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.