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Tumor Tissue Gene Panel With MSI And TMB

Virginia rates for HCPCS 0334U

Guides treatment choice in solid tumors by identifying the genetic changes driving the cancer. Preserved, formalin-fixed tumor tissue is sequenced across at least eighty-four genes. The service also reports microsatellite instability and tumor mutational burden — two whole-tumor measures counted outside that gene total, which help predict response to immunotherapy.

Rates data updated July 2026.

How much does Tumor Tissue Gene Panel With MSI And TMB cost?

$2,399

Typical negotiated rate. In Virginia, July 2026.

Insurers have agreed to pay about $2,399 for this service. The price depends on where it is billed: about $2,188 from a physician practice, and about $4,467 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$2,188$1,230 to $2,455
FacilityA hospital or hospital-owned outpatient department$4,467$2,951 to $6,607

How much rates vary

Facilitymedian $4,467 · 10th to 90th $2,188 to $13,804Professionalmedian $2,188 · 10th to 90th $1,175 to $4,467
$2K$5K$10Kfacility $4,467professional $2,188

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,187.76
Median
$6,456.54
Typical High
$7,244.36
Aetna
Setting
Professional
Modifier
Global
Typical Low
$2,187.76
Median
$2,398.83
Typical High
$6,606.93
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$11,748.98
Median
$15,135.61
Typical High
$18,197.01
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$1,174.90
Median
$1,174.90
Typical High
$1,949.84
CareFirst
Setting
Professional
Modifier
Global
Typical Low
$2,630.27
Median
$2,951.21
Typical High
$3,235.94
Cigna
Setting
Facility
Modifier
Global
Typical Low
$5,754.40
Median
$7,244.36
Typical High
$15,488.17
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$3,467.37
Median
$3,890.45
Typical High
$4,897.79
Medcost
Setting
Facility
Modifier
Global
Typical Low
$2,187.76
Median
$2,818.38
Typical High
$5,011.87
Medcost
Setting
Professional
Modifier
Global
Typical Low
$1,905.46
Median
$1,905.46
Typical High
$1,905.46
Sentara
Setting
Facility
Modifier
Global
Typical Low
$2,398.83
Median
$3,981.07
Typical High
$7,079.46
Sentara
Setting
Professional
Modifier
Global
Typical Low
$2,398.83
Median
$3,981.07
Typical High
$7,244.36
United
Setting
Facility
Modifier
Global
Typical Low
$1,479.11
Median
$2,951.21
Typical High
$3,467.37
United
Setting
Professional
Modifier
Global
Typical Low
$1,230.27
Median
$1,445.44
Typical High
$3,388.44

Where Virginia sits

The same service costs 6.5 times more in Alaska than in Montana. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Virginia· 34th of 51

$2,399

AK $7,943MT $1,230

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.