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Tumor Tissue Gene Panel With MSI And TMB

South Carolina rates for HCPCS 0334U

Guides treatment choice in solid tumors by identifying the genetic changes driving the cancer. Preserved, formalin-fixed tumor tissue is sequenced across at least eighty-four genes. The service also reports microsatellite instability and tumor mutational burden — two whole-tumor measures counted outside that gene total, which help predict response to immunotherapy.

Rates data updated July 2026.

How much does Tumor Tissue Gene Panel With MSI And TMB cost?

$2,344

Typical negotiated rate. In South Carolina, July 2026.

Insurers have agreed to pay about $2,344 for this service. The price depends on where it is billed: about $2,291 from a physician practice, and about $8,710 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$2,291$2,291 to $2,344
FacilityA hospital or hospital-owned outpatient department$8,710$2,344 to $11,220

How much rates vary

Facilitymedian $8,710 · 10th to 90th $2,291 to $13,804Professionalmedian $2,291 · 10th to 90th $1,738 to $2,512
$50$200$1K$5K$20Kfacility $8,710professional $2,291

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,290.87
Median
$8,709.64
Typical High
$13,803.84
Aetna
Setting
Professional
Modifier
Global
Typical Low
$2,290.87
Median
$2,290.87
Typical High
$2,398.83
BCBS
Setting
Facility
Modifier
Global
Typical Low
$10,715.19
Median
$10,715.19
Typical High
$10,715.19
BCBS
Setting
Professional
Modifier
Global
Typical Low
$3,467.37
Median
$3,715.35
Typical High
$4,897.79
Cigna
Setting
Facility
Modifier
Global
Typical Low
$6,606.93
Median
$10,471.29
Typical High
$19,952.62
Medcost
Setting
Facility
Modifier
Global
Typical Low
$2,041.74
Median
$2,511.89
Typical High
$3,890.45
Molina
Setting
Professional
Modifier
Global
Typical Low
$30.20
Median
$30.20
Typical High
$30.20
United
Setting
Facility
Modifier
Global
Typical Low
$2,951.21
Median
$2,951.21
Typical High
$3,162.28
United
Setting
Professional
Modifier
Global
Typical Low
$1,230.27
Median
$1,737.80
Typical High
$2,951.21

Where South Carolina sits

The same service costs 6.5 times more in Alaska than in Montana. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Carolina· 38th of 51

$2,344

AK $7,943MT $1,230

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.