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Tumor Tissue Gene Panel With MSI And TMB

Pennsylvania rates for HCPCS 0334U

Guides treatment choice in solid tumors by identifying the genetic changes driving the cancer. Preserved, formalin-fixed tumor tissue is sequenced across at least eighty-four genes. The service also reports microsatellite instability and tumor mutational burden — two whole-tumor measures counted outside that gene total, which help predict response to immunotherapy.

Rates data updated July 2026.

How much does Tumor Tissue Gene Panel With MSI And TMB cost?

$2,455

Typical negotiated rate. In Pennsylvania, July 2026.

Insurers have agreed to pay about $2,455 for this service. The price depends on where it is billed: about $2,344 from a physician practice, and about $5,623 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$2,344$1,738 to $2,455
FacilityA hospital or hospital-owned outpatient department$5,623$3,548 to $7,943

How much rates vary

Facilitymedian $5,623 · 10th to 90th $2,455 to $10,471Professionalmedian $2,344 · 10th to 90th $1,585 to $2,951
$2K$5K$10Kfacility $5,623professional $2,344

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,454.71
Median
$5,623.41
Typical High
$12,882.50
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,584.89
Median
$2,344.23
Typical High
$2,754.23
Capital Blue Cross
Setting
Professional
Modifier
Global
Typical Low
$2,754.23
Median
$2,754.23
Typical High
$2,754.23
Cigna
Setting
Facility
Modifier
Global
Typical Low
$2,511.89
Median
$4,466.84
Typical High
$7,943.28
Cigna
Setting
Professional
Modifier
Global
Typical Low
$16,982.44
Median
$16,982.44
Typical High
$16,982.44
Emblem Health
Setting
Professional
Modifier
Global
Typical Low
$4,570.88
Median
$4,570.88
Typical High
$5,011.87
Geisinger
Setting
Facility
Modifier
Global
Typical Low
$3,467.37
Median
$3,467.37
Typical High
$3,467.37
Geisinger
Setting
Professional
Modifier
Global
Typical Low
$2,187.76
Median
$3,801.89
Typical High
$6,165.95
Martin's Point
Setting
Facility
Modifier
Global
Typical Low
$2,754.23
Median
$5,623.41
Typical High
$10,471.29
Martin's Point
Setting
Professional
Modifier
Global
Typical Low
$1,584.89
Median
$2,344.23
Typical High
$8,709.64
United
Setting
Facility
Modifier
Global
Typical Low
$1,737.80
Median
$1,737.80
Typical High
$1,737.80
United
Setting
Professional
Modifier
Global
Typical Low
$1,230.27
Median
$1,737.80
Typical High
$4,073.80

Where Pennsylvania sits

The same service costs 6.5 times more in Alaska than in Montana. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Pennsylvania· 31st of 51

$2,455

AK $7,943MT $1,230

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.