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Tumor Tissue Gene Panel With MSI And TMB

Oklahoma rates for HCPCS 0334U

Guides treatment choice in solid tumors by identifying the genetic changes driving the cancer. Preserved, formalin-fixed tumor tissue is sequenced across at least eighty-four genes. The service also reports microsatellite instability and tumor mutational burden — two whole-tumor measures counted outside that gene total, which help predict response to immunotherapy.

Rates data updated July 2026.

How much does Tumor Tissue Gene Panel With MSI And TMB cost?

$2,570

Typical negotiated rate. In Oklahoma, July 2026.

Insurers have agreed to pay about $2,570 for this service. The price depends on where it is billed: about $2,344 from a physician practice, and about $3,467 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$2,344$1,230 to $3,090
FacilityA hospital or hospital-owned outpatient department$3,467$2,344 to $4,169

How much rates vary

Facilitymedian $3,467 · 10th to 90th $2,188 to $8,913Professionalmedian $2,344 · 10th to 90th $1,230 to $3,715
$2K$5K$10K$20Kfacility $3,467professional $2,344

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,344.23
Median
$3,467.37
Typical High
$8,912.51
Aetna
Setting
Professional
Modifier
Global
Typical Low
$2,187.76
Median
$2,344.23
Typical High
$3,715.35
BCBS
Setting
Professional
Modifier
Global
Typical Low
$2,754.23
Median
$2,754.23
Typical High
$2,754.23
Cigna
Setting
Facility
Modifier
Global
Typical Low
$3,090.30
Median
$9,332.54
Typical High
$9,549.93
Cigna
Setting
Professional
Modifier
Global
Typical Low
$4,265.80
Median
$4,265.80
Typical High
$5,128.61
Medica
Setting
Facility
Modifier
Global
Typical Low
$2,089.30
Median
$3,019.95
Typical High
$6,025.60
Medica
Setting
Professional
Modifier
Global
Typical Low
$1,230.27
Median
$1,230.27
Typical High
$3,715.35
United
Setting
Facility
Modifier
Global
Typical Low
$1,230.27
Median
$2,951.21
Typical High
$3,981.07
United
Setting
Professional
Modifier
Global
Typical Low
$1,230.27
Median
$1,230.27
Typical High
$1,905.46

Where Oklahoma sits

The same service costs 6.5 times more in Alaska than in Montana. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Oklahoma· 27th of 51

$2,570

AK $7,943MT $1,230

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.