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Tumor Tissue Gene Panel With MSI And TMB

North Carolina rates for HCPCS 0334U

Guides treatment choice in solid tumors by identifying the genetic changes driving the cancer. Preserved, formalin-fixed tumor tissue is sequenced across at least eighty-four genes. The service also reports microsatellite instability and tumor mutational burden — two whole-tumor measures counted outside that gene total, which help predict response to immunotherapy.

Rates data updated July 2026.

How much does Tumor Tissue Gene Panel With MSI And TMB cost?

$2,344

Typical negotiated rate. In North Carolina, July 2026.

Insurers have agreed to pay about $2,344 for this service. The price depends on where it is billed: about $2,344 from a physician practice, and about $2,570 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$2,344$2,344 to $3,467
FacilityA hospital or hospital-owned outpatient department$2,570$2,344 to $3,715

How much rates vary

Facilitymedian $2,570 · 10th to 90th $2,344 to $7,586Professionalmedian $2,344 · 10th to 90th $1,950 to $4,898
$2K$5K$10Kfacility $2,570professional $2,344

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,344.23
Median
$2,344.23
Typical High
$6,456.54
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,949.84
Median
$2,344.23
Typical High
$2,344.23
BCBS
Setting
Professional
Modifier
Global
Typical Low
$2,454.71
Median
$3,467.37
Typical High
$5,623.41
Cigna
Setting
Facility
Modifier
Global
Typical Low
$2,884.03
Median
$7,585.78
Typical High
$15,848.93
Medcost
Setting
Facility
Modifier
Global
Typical Low
$2,290.87
Median
$2,630.27
Typical High
$4,073.80
Medcost
Setting
Professional
Modifier
Global
Typical Low
$1,905.46
Median
$1,905.46
Typical High
$1,905.46
United
Setting
Facility
Modifier
Global
Typical Low
$1,737.80
Median
$3,467.37
Typical High
$3,548.13
United
Setting
Professional
Modifier
Global
Typical Low
$1,230.27
Median
$1,737.80
Typical High
$3,235.94
Wellcare
Setting
Facility
Modifier
Global
Typical Low
$16,595.87
Median
$16,595.87
Typical High
$16,595.87
Wellcare
Setting
Professional
Modifier
Global
Typical Low
$17,378.01
Median
$17,378.01
Typical High
$26,302.68

Where North Carolina sits

The same service costs 6.5 times more in Alaska than in Montana. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

North Carolina· 37th of 51

$2,344

AK $7,943MT $1,230

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.