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Tumor Tissue Gene Panel With MSI And TMB

Missouri rates for HCPCS 0334U

Guides treatment choice in solid tumors by identifying the genetic changes driving the cancer. Preserved, formalin-fixed tumor tissue is sequenced across at least eighty-four genes. The service also reports microsatellite instability and tumor mutational burden — two whole-tumor measures counted outside that gene total, which help predict response to immunotherapy.

Rates data updated July 2026.

How much does Tumor Tissue Gene Panel With MSI And TMB cost?

$2,818

Typical negotiated rate. In Missouri, July 2026.

Insurers have agreed to pay about $2,818 for this service. The price depends on where it is billed: about $2,455 from a physician practice, and about $5,129 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$2,455$1,230 to $3,236
FacilityA hospital or hospital-owned outpatient department$5,129$2,884 to $6,026

How much rates vary

Facilitymedian $5,129 · 10th to 90th $2,455 to $6,761Professionalmedian $2,455 · 10th to 90th $1,175 to $5,012
$1K$2K$5K$10Kfacility $5,129professional $2,455

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,818.38
Median
$5,128.61
Typical High
$6,760.83
Aetna
Setting
Professional
Modifier
Global
Typical Low
$2,454.71
Median
$2,511.89
Typical High
$5,888.44
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$1,174.90
Median
$1,202.26
Typical High
$4,786.30
Cigna
Setting
Facility
Modifier
Global
Typical Low
$4,786.30
Median
$7,413.10
Typical High
$18,197.01
Medica
Setting
Facility
Modifier
Global
Typical Low
$2,454.71
Median
$3,715.35
Typical High
$16,218.10
Medica
Setting
Professional
Modifier
Global
Typical Low
$1,230.27
Median
$1,737.80
Typical High
$4,677.35
United
Setting
Facility
Modifier
Global
Typical Low
$1,047.13
Median
$3,467.37
Typical High
$4,168.69
United
Setting
Professional
Modifier
Global
Typical Low
$1,230.27
Median
$1,737.80
Typical High
$3,388.44

Where Missouri sits

The same service costs 6.5 times more in Alaska than in Montana. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 24th of 51

$2,818

AK $7,943MT $1,230

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.