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Tumor Tissue Gene Panel With MSI And TMB

Minnesota rates for HCPCS 0334U

Guides treatment choice in solid tumors by identifying the genetic changes driving the cancer. Preserved, formalin-fixed tumor tissue is sequenced across at least eighty-four genes. The service also reports microsatellite instability and tumor mutational burden — two whole-tumor measures counted outside that gene total, which help predict response to immunotherapy.

Rates data updated July 2026.

How much does Tumor Tissue Gene Panel With MSI And TMB cost?

$3,467

Typical negotiated rate. In Minnesota, July 2026.

Insurers have agreed to pay about $3,467 for this service. The price depends on where it is billed: about $3,467 from a physician practice, and about $9,333 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$3,467$3,162 to $3,981
FacilityA hospital or hospital-owned outpatient department$9,333$3,467 to $13,804

How much rates vary

Facilitymedian $9,333 · 10th to 90th $3,467 to $25,704Professionalmedian $3,467 · 10th to 90th $2,818 to $5,129
$2K$5K$10K$20Kfacility $9,333professional $3,467

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$10,000.00
Median
$10,000.00
Typical High
$10,000.00
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,905.46
Median
$2,238.72
Typical High
$3,548.13
BCBS
Setting
Facility
Modifier
Global
Typical Low
$3,311.31
Median
$3,467.37
Typical High
$3,467.37
BCBS
Setting
Professional
Modifier
Global
Typical Low
$2,818.38
Median
$3,467.37
Typical High
$3,467.37
Cigna
Setting
Facility
Modifier
Global
Typical Low
$7,762.47
Median
$12,022.64
Typical High
$32,359.37
Cigna
Setting
Professional
Modifier
Global
Typical Low
$4,073.80
Median
$5,128.61
Typical High
$7,244.36
Health Partners
Setting
Facility
Modifier
Global
Typical Low
$9,120.11
Median
$11,220.18
Typical High
$25,703.96
Health Partners
Setting
Professional
Modifier
Global
Typical Low
$3,981.07
Median
$3,981.07
Typical High
$6,760.83
Medica
Setting
Facility
Modifier
Global
Typical Low
$2,187.76
Median
$6,165.95
Typical High
$9,120.11
Medica
Setting
Professional
Modifier
Global
Typical Low
$1,230.27
Median
$1,737.80
Typical High
$6,165.95
United
Setting
Facility
Modifier
Global
Typical Low
$3,981.07
Median
$3,981.07
Typical High
$3,981.07
United
Setting
Professional
Modifier
Global
Typical Low
$1,479.11
Median
$2,951.21
Typical High
$6,456.54

Where Minnesota sits

The same service costs 6.5 times more in Alaska than in Montana. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Minnesota· 14th of 51

$3,467

AK $7,943MT $1,230

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.