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Tumor Tissue Gene Panel With MSI And TMB

Michigan rates for HCPCS 0334U

Guides treatment choice in solid tumors by identifying the genetic changes driving the cancer. Preserved, formalin-fixed tumor tissue is sequenced across at least eighty-four genes. The service also reports microsatellite instability and tumor mutational burden — two whole-tumor measures counted outside that gene total, which help predict response to immunotherapy.

Rates data updated July 2026.

How much does Tumor Tissue Gene Panel With MSI And TMB cost?

$2,754

Typical negotiated rate. In Michigan, July 2026.

Insurers have agreed to pay about $2,754 for this service. The price depends on where it is billed: about $2,754 from a physician practice, and about $2,754 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$2,754$2,399 to $3,090
FacilityA hospital or hospital-owned outpatient department$2,754$2,754 to $4,365

How much rates vary

Facilitymedian $2,754 · 10th to 90th $2,754 to $5,129Professionalmedian $2,754 · 10th to 90th $1,585 to $3,467
$2K$5Kfacility $2,754professional $2,754

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,754.23
Median
$2,754.23
Typical High
$5,128.61
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,584.89
Median
$2,754.23
Typical High
$2,818.38
BCBS
Setting
Facility
Modifier
Global
Typical Low
$3,090.30
Median
$4,677.35
Typical High
$8,128.31
BCBS
Setting
Professional
Modifier
Global
Typical Low
$2,951.21
Median
$3,090.30
Typical High
$3,090.30
Cigna
Setting
Professional
Modifier
Global
Typical Low
$3,548.13
Median
$4,073.80
Typical High
$4,466.84
Health Alliance Plan
Setting
Facility
Modifier
Global
Typical Low
$2,754.23
Median
$3,019.95
Typical High
$7,413.10
Health Alliance Plan
Setting
Professional
Modifier
Global
Typical Low
$2,344.23
Median
$3,090.30
Typical High
$4,265.80
Priority Health
Setting
Professional
Modifier
Global
Typical Low
$3,548.13
Median
$3,548.13
Typical High
$4,073.80
United
Setting
Facility
Modifier
Global
Typical Low
$2,951.21
Median
$3,467.37
Typical High
$5,248.07
United
Setting
Professional
Modifier
Global
Typical Low
$1,230.27
Median
$1,737.80
Typical High
$2,951.21

Where Michigan sits

The same service costs 6.5 times more in Alaska than in Montana. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Michigan· 25th of 51

$2,754

AK $7,943MT $1,230

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.