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Tumor Tissue Gene Panel With MSI And TMB

Maine rates for HCPCS 0334U

Guides treatment choice in solid tumors by identifying the genetic changes driving the cancer. Preserved, formalin-fixed tumor tissue is sequenced across at least eighty-four genes. The service also reports microsatellite instability and tumor mutational burden — two whole-tumor measures counted outside that gene total, which help predict response to immunotherapy.

Rates data updated July 2026.

How much does Tumor Tissue Gene Panel With MSI And TMB cost?

$3,467

Typical negotiated rate. In Maine, July 2026.

Insurers have agreed to pay about $3,467 for this service. The price depends on where it is billed: about $3,467 from a physician practice, and about $5,623 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$3,467$2,344 to $3,467
FacilityA hospital or hospital-owned outpatient department$5,623$3,467 to $15,849

How much rates vary

Facilitymedian $5,623 · 10th to 90th $3,467 to $18,621Professionalmedian $3,467 · 10th to 90th $1,738 to $3,548
$2K$5K$10K$20Kfacility $5,623professional $3,467

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$3,467.37
Median
$3,467.37
Typical High
$8,709.64
Aetna
Setting
Professional
Modifier
Global
Typical Low
$2,344.23
Median
$2,344.23
Typical High
$2,344.23
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$16,218.10
Median
$18,620.87
Typical High
$20,417.38
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$1,174.90
Median
$1,778.28
Typical High
$2,754.23
Cigna
Setting
Facility
Modifier
Global
Typical Low
$7,943.28
Median
$7,943.28
Typical High
$7,943.28
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$3,467.37
Median
$3,467.37
Typical High
$4,168.69
Martin's Point
Setting
Facility
Modifier
Global
Typical Low
$3,467.37
Median
$3,467.37
Typical High
$8,709.64
Martin's Point
Setting
Professional
Modifier
Global
Typical Low
$2,344.23
Median
$2,344.23
Typical High
$3,467.37
United
Setting
Professional
Modifier
Global
Typical Low
$1,737.80
Median
$3,467.37
Typical High
$4,365.16

Where Maine sits

The same service costs 6.5 times more in Alaska than in Montana. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Maine· 9th of 51

$3,467

AK $7,943MT $1,230

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.