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Tumor Tissue Gene Panel With MSI And TMB

Indiana rates for HCPCS 0334U

Guides treatment choice in solid tumors by identifying the genetic changes driving the cancer. Preserved, formalin-fixed tumor tissue is sequenced across at least eighty-four genes. The service also reports microsatellite instability and tumor mutational burden — two whole-tumor measures counted outside that gene total, which help predict response to immunotherapy.

Rates data updated July 2026.

How much does Tumor Tissue Gene Panel With MSI And TMB cost?

$3,467

Typical negotiated rate. In Indiana, July 2026.

Insurers have agreed to pay about $3,467 for this service. The price depends on where it is billed: about $2,399 from a physician practice, and about $3,981 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$2,399$1,738 to $2,754
FacilityA hospital or hospital-owned outpatient department$3,981$3,467 to $7,762

How much rates vary

Facilitymedian $3,981 · 10th to 90th $3,467 to $10,471Professionalmedian $2,399 · 10th to 90th $1,175 to $3,890
$2K$5K$10K$20Kfacility $3,981professional $2,399

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$3,090.30
Median
$5,495.41
Typical High
$10,471.29
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,995.26
Median
$2,398.83
Typical High
$2,818.38
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$3,467.37
Median
$3,467.37
Typical High
$10,471.29
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$1,174.90
Median
$1,174.90
Typical High
$7,079.46
CareSource
Setting
Facility
Modifier
Global
Typical Low
$3,388.44
Median
$51,286.14
Typical High
$75,857.76
Cigna
Setting
Facility
Modifier
Global
Typical Low
$2,290.87
Median
$5,754.40
Typical High
$9,549.93
Cigna
Setting
Professional
Modifier
Global
Typical Low
$3,981.07
Median
$4,265.80
Typical High
$5,128.61
United
Setting
Facility
Modifier
Global
Typical Low
$2,951.21
Median
$2,951.21
Typical High
$4,168.69
United
Setting
Professional
Modifier
Global
Typical Low
$1,230.27
Median
$1,737.80
Typical High
$3,235.94

Where Indiana sits

The same service costs 6.5 times more in Alaska than in Montana. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Indiana· 15th of 51

$3,467

AK $7,943MT $1,230

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.