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Tumor Tissue Gene Panel With MSI And TMB

Illinois rates for HCPCS 0334U

Guides treatment choice in solid tumors by identifying the genetic changes driving the cancer. Preserved, formalin-fixed tumor tissue is sequenced across at least eighty-four genes. The service also reports microsatellite instability and tumor mutational burden — two whole-tumor measures counted outside that gene total, which help predict response to immunotherapy.

Rates data updated July 2026.

How much does Tumor Tissue Gene Panel With MSI And TMB cost?

$2,818

Typical negotiated rate. In Illinois, July 2026.

Insurers have agreed to pay about $2,818 for this service. The price depends on where it is billed: about $2,455 from a physician practice, and about $4,571 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$2,455$2,138 to $2,951
FacilityA hospital or hospital-owned outpatient department$4,571$3,020 to $6,026

How much rates vary

Facilitymedian $4,571 · 10th to 90th $2,399 to $7,413Professionalmedian $2,455 · 10th to 90th $1,585 to $6,026
$500$1K$2K$5K$10Kfacility $4,571professional $2,455

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,398.83
Median
$4,570.88
Typical High
$7,079.46
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,819.70
Median
$2,454.71
Typical High
$6,025.60
BCBS
Setting
Facility
Modifier
Global
Typical Low
$4,168.69
Median
$4,677.35
Typical High
$5,754.40
BCBS
Setting
Professional
Modifier
Global
Typical Low
$3,467.37
Median
$3,467.37
Typical High
$3,467.37
Cigna
Setting
Facility
Modifier
Global
Typical Low
$4,786.30
Median
$8,128.31
Typical High
$17,782.79
Cigna
Setting
Professional
Modifier
Global
Typical Low
$4,073.80
Median
$4,265.80
Typical High
$5,128.61
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$346.74
Median
$4,677.35
Typical High
$6,309.57
Hally Health
Setting
Facility
Modifier
Global
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$4,570.88
Median
$4,570.88
Typical High
$4,570.88
United
Setting
Facility
Modifier
Global
Typical Low
$1,737.80
Median
$3,467.37
Typical High
$7,079.46
United
Setting
Professional
Modifier
Global
Typical Low
$1,230.27
Median
$1,737.80
Typical High
$2,951.21

Where Illinois sits

The same service costs 6.5 times more in Alaska than in Montana. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Illinois· 23rd of 51

$2,818

AK $7,943MT $1,230

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.